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    fras1.L Fraser extracellular matrix complex subunit 1 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 108719644, updated on 4-Nov-2024

    Summary

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    Official Symbol
    fras1.L
    Official Full Name
    Fraser extracellular matrix complex subunit 1 L homeolog
    Primary source
    Xenbase:XB-GENE-17341205
    Locus tag
    XELAEV_18005869mg
    See related
    EnsemblRapid:ENSXLAG00005035158 AllianceGenome:Xenbase:XB-GENE-17341205
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Summary
    Human ortholog(s) of this gene implicated in Fraser syndrome 1. Orthologous to human FRAS1 (Fraser extracellular matrix complex subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See fras1.L in Genome Data Viewer
    Location:
    chromosome: 1L
    Exon count:
    76
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (87735865..88005380)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (76833687..77097743)

    Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121403519 Neighboring gene mitochondrial ribosomal protein L1 L homeolog Neighboring gene annexin A3 L homeolog Neighboring gene protein tyrosine phosphatase non-receptor type 9-like L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    extracellular matrix organizing protein FRAS1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      87735865..88005380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041591087.1 → XP_041447021.1  extracellular matrix organizing protein FRAS1 isoform X2

      UniProtKB/TrEMBL
      A0A8J1MZV6, A0A974I387
      Related
      ENSXLAP00005105248.1, ENSXLAT00005107296.1
      Conserved Domains (6) summary
      pfam03302
      Location:676 → 1041
      VSP; Giardia variant-specific surface protein
      smart00214
      Location:390 → 436
      VWC; von Willebrand factor (vWF) type C domain
      cd00064
      Location:1021 → 1067
      FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
      TIGR00845
      Location:2812 → 3063
      caca; sodium/calcium exchanger 1
      pfam00093
      Location:114 → 171
      VWC; von Willebrand factor type C domain
      cl02522
      Location:3057 → 3149
      Calx-beta; Calx-beta domain

    2. XM_041591088.1 → XP_041447022.1  extracellular matrix organizing protein FRAS1 isoform X3

      UniProtKB/TrEMBL
      A0A8J1MZ04, A0A974I387
      Related
      ENSXLAP00005105670.1, ENSXLAT00005107730.1
      Conserved Domains (6) summary
      pfam03302
      Location:657 → 1022
      VSP; Giardia variant-specific surface protein
      smart00214
      Location:371 → 417
      VWC; von Willebrand factor (vWF) type C domain
      cd00064
      Location:1002 → 1048
      FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
      TIGR00845
      Location:2793 → 3044
      caca; sodium/calcium exchanger 1
      pfam00093
      Location:95 → 152
      VWC; von Willebrand factor type C domain
      cl02522
      Location:3038 → 3130
      Calx-beta; Calx-beta domain

    3. XM_041591086.1 → XP_041447020.1  extracellular matrix organizing protein FRAS1 isoform X1

      UniProtKB/TrEMBL
      A0A8J1N1B0, A0A974I387
      Related
      ENSXLAP00005105113.1, ENSXLAT00005107158.1
      Conserved Domains (6) summary
      pfam03302
      Location:685 → 1050
      VSP; Giardia variant-specific surface protein
      smart00214
      Location:399 → 445
      VWC; von Willebrand factor (vWF) type C domain
      cd00064
      Location:1030 → 1076
      FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
      TIGR00845
      Location:2821 → 3072
      caca; sodium/calcium exchanger 1
      pfam00093
      Location:123 → 180
      VWC; von Willebrand factor type C domain
      cl02522
      Location:3066 → 3158
      Calx-beta; Calx-beta domain
    Nucleotide Protein Strain
    Heading Accession and Version

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