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    PRAL p53 regulation associated lncRNA [ Homo sapiens (human) ]

    Gene ID: 109245082, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PRALprovided by HGNC
    Official Full Name
    p53 regulation associated lncRNAprovided by HGNC
    Primary source
    HGNC:HGNC:52646
    See related
    AllianceGenome:HGNC:52646
    Gene type
    ncRNA
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    lncRNA-PRAL
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    17p13.1

    Bibliography

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    Related articles in PubMed

    1. Expression of Long Non-Coding RNA PRAL as a Potential Biomarker for Diagnosis in Non-Small-Cell Lung Cancer Patients is Associated with the Inhibition of Cell Proliferation and Metastasis. Wang H, et al. Clin Lab, 2018 Sep 1. PMID 30274002
    2. P53 Regulation-Association Long Non-Coding RNA (LncRNA PRAL) Inhibits Cell Proliferation by Regulation of P53 in Human Lung Cancer. Su P, et al. Med Sci Monit, 2017 Apr 11. PMID 28396580, Free PMC Article
    3. Systemic genome screening identifies the outcome associated focal loss of long noncoding RNA PRAL in hepatocellular carcinoma. Zhou CC, et al. Hepatology, 2016 Mar. PMID 26663434
    4. LncRNA PRAL is closely related to clinical prognosis of multiple myeloma and the bortezomib sensitivity. Xiao G, et al. Exp Cell Res, 2018 Sep 15. PMID 29944867

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Over-expression of PRAL blocked proliferation, migration, and invasion in non-small-cell lung carcinoma cell lines.
      Title: Expression of Long Non-Coding RNA PRAL as a Potential Biomarker for Diagnosis in Non-Small-Cell Lung Cancer Patients is Associated with the Inhibition of Cell Proliferation and Metastasis.
    2. Overexpression of PRAL inhibited cell proliferation by upregulating the expression of P53. Results indicate that PRAL might be a tumor suppressor in lung cancer and thus provides novel clues for the diagnosis and treatment for lung cancer in clinical practice.
      Title: P53 Regulation-Association Long Non-Coding RNA (LncRNA PRAL) Inhibits Cell Proliferation by Regulation of P53 in Human Lung Cancer.
    Submit: New GeneRIF Correction
    Nucleotide Protein
    Heading Accession and Version

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