Nudt19 nudix hydrolase 19 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nudt19provided by MGI
Official Full Name: nudix hydrolase 19provided by MGI
Primary source: MGI:MGI:94203
See related: Ensembl:ENSMUSG00000034875 AllianceGenome:MGI:94203
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: D7Rp2; RP2-r; RP2-s; D7Rp2e; D7Rp2-r; D7Rp2-s
Summary: Enables magnesium ion binding activity. Involved in acyl-CoA metabolic process and coenzyme A catabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; cerebral cortex; liver; male reproductive gland or organ; and metanephros. Orthologous to human NUDT19 (nudix hydrolase 19). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in kidney adult (RPKM 83.0), adrenal adult (RPKM 55.6) and 27 other tissues See more
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 7 B2; 7 21.37 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (35246610..35258345, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (35547185..35558643, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Nudix hydrolase NUDT19 regulates mitochondrial function and ATP production in murine hepatocytes.
Title: Nudix hydrolase NUDT19 regulates mitochondrial function and ATP production in murine hepatocytes.
The isolation and characterization of D7RP2e in mouse kidney peroxisomes is reported.
Title: Proteomic analysis of mouse kidney peroxisomes: identification of RP2p as a peroxisomal nudix hydrolase with acyl-CoA diphosphatase activity.

Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)
Targeted (2)

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

Nudt19 (e-PCR), detects polymorphism
- UniSTS:508536

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables coenzyme A diphosphatase activity	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in butyryl-CoA catabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in coenzyme A catabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in malonyl-CoA catabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in medium-chain fatty-acyl-CoA catabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in propionyl-CoA metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in succinyl-CoA catabolic process	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	HDA more info	PubMed
located_in peroxisome	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: acyl-coenzyme A diphosphatase NUDT19

Names: RP2p; androgen regulated gene RP2; androgen-regulated protein RP2; nucleoside diphosphate-linked moiety X motif 19, mitochondrial; nudix (nucleoside diphosphate linked moiety X)-type motif 19; nudix motif 19; renal CoA diphosphohydrolase; testosterone-regulated RP2 protein

NP_149071.2

EC 3.6.1.77

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.