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    KDM2B lysine demethylase 2B [ Phyllostomus discolor (pale spear-nosed bat) ]

    Gene ID: 114509357, updated on 30-Mar-2024

    Summary

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    Gene symbol
    KDM2B
    Gene description
    lysine demethylase 2B
    See related
    EnsemblRapid:ENSPDIG00005015018
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Phyllostomus discolor
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Phyllostominae; Phyllostomus
    Orthologs
    human mouse all
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    Genomic context

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    See KDM2B in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    101 current mPhyDis1.pri.v3 (GCF_004126475.2) 13 NC_040915.2 (44708221..44810697)
    100 previous assembly mPhyDis1_v1.p (GCF_004126475.1) 13 NC_040915.1 (2150836..2252215)

    Chromosome 13 - NC_040915.2Genomic Context describing neighboring genes Neighboring gene ORAI calcium release-activated calcium modulator 1 Neighboring gene U6 spliceosomal RNA Neighboring gene ring finger protein 34 Neighboring gene anaphase promoting complex subunit 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone demethylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein demethylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lysine-specific demethylase 2B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Phyllostomus discolor Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mPhyDis1.pri.v3

    Genomic

    1. NC_040915.2 Reference mPhyDis1.pri.v3

      Range
      44708221..44810697
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036014584.1 → XP_035870477.1  lysine-specific demethylase 2B isoform X3

      UniProtKB/TrEMBL
      A0A7E6CUC0, A0A833YW16
      Conserved Domains (10) summary
      PTZ00449
      Location:691 → 927
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1092 → 1281
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:151 → 226
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1076 → 1100
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:632 → 693
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:586 → 622
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1042 → 1080
      F-box-like
      pfam17811
      Location:303 → 338
      JHD; Jumonji helical domain
      cd21785
      Location:478 → 544
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:198 → 304
      cupin_RmlC-like; RmlC-like cupin superfamily

    2. XM_036014585.1 → XP_035870478.1  lysine-specific demethylase 2B isoform X4

      UniProtKB/TrEMBL
      A0A7E6CTV8, A0A833YW16
      Related
      ENSPDIP00005021484.1, ENSPDIT00005024774.2
      Conserved Domains (10) summary
      PTZ00449
      Location:691 → 924
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1089 → 1278
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:151 → 226
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1073 → 1097
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:632 → 693
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:586 → 622
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1039 → 1077
      F-box-like
      pfam17811
      Location:303 → 338
      JHD; Jumonji helical domain
      cd21785
      Location:478 → 544
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:198 → 304
      cupin_RmlC-like; RmlC-like cupin superfamily

    3. XM_036014586.1 → XP_035870479.1  lysine-specific demethylase 2B isoform X5

      UniProtKB/TrEMBL
      A0A7E6CWN8, A0A833YW16
      Conserved Domains (10) summary
      PTZ00449
      Location:685 → 921
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1086 → 1275
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:145 → 220
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1070 → 1094
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:626 → 687
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:580 → 616
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1036 → 1074
      F-box-like
      pfam17811
      Location:297 → 332
      JHD; Jumonji helical domain
      cd21785
      Location:472 → 538
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:192 → 298
      cupin_RmlC-like; RmlC-like cupin superfamily

    4. XM_036014587.1 → XP_035870480.1  lysine-specific demethylase 2B isoform X6

      UniProtKB/TrEMBL
      A0A7E6CTV0, A0A833YW16
      Related
      ENSPDIP00005037112.1, ENSPDIT00005043782.1
      Conserved Domains (10) summary
      PTZ00449
      Location:685 → 918
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1083 → 1272
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:145 → 220
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1067 → 1091
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:626 → 687
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:580 → 616
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1033 → 1071
      F-box-like
      pfam17811
      Location:297 → 332
      JHD; Jumonji helical domain
      cd21785
      Location:472 → 538
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:192 → 298
      cupin_RmlC-like; RmlC-like cupin superfamily

    5. XM_036014582.1 → XP_035870475.1  lysine-specific demethylase 2B isoform X1

      UniProtKB/TrEMBL
      A0A7E6CTU4, A0A833YW16
      Conserved Domains (10) summary
      PTZ00449
      Location:733 → 969
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1134 → 1323
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:193 → 268
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1118 → 1142
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:674 → 735
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:628 → 664
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1084 → 1122
      F-box-like
      pfam17811
      Location:345 → 380
      JHD; Jumonji helical domain
      cd21785
      Location:520 → 586
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:240 → 346
      cupin_RmlC-like; RmlC-like cupin superfamily

    6. XM_036014583.1 → XP_035870476.1  lysine-specific demethylase 2B isoform X2

      UniProtKB/TrEMBL
      A0A7E6CUK4, A0A833YW16
      Conserved Domains (10) summary
      PTZ00449
      Location:733 → 966
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1131 → 1320
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:193 → 268
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1115 → 1139
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:674 → 735
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:628 → 664
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1081 → 1119
      F-box-like
      pfam17811
      Location:345 → 380
      JHD; Jumonji helical domain
      cd21785
      Location:520 → 586
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:240 → 346
      cupin_RmlC-like; RmlC-like cupin superfamily

    7. XM_036014588.1 → XP_035870481.1  lysine-specific demethylase 2B isoform X7

      UniProtKB/TrEMBL
      A0A7E6CUD3, A0A833YW16
      Conserved Domains (9) summary
      PTZ00449
      Location:491 → 727
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:892 → 1081
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:876 → 900
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:432 → 493
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:386 → 422
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:842 → 880
      F-box-like
      pfam17811
      Location:103 → 138
      JHD; Jumonji helical domain
      cd21785
      Location:278 → 344
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:1 → 104
      cupin_RmlC-like; RmlC-like cupin superfamily

    8. XM_036014589.1 → XP_035870482.1  lysine-specific demethylase 2B isoform X7

      UniProtKB/TrEMBL
      A0A7E6CUD3, A0A833YW16
      Conserved Domains (9) summary
      PTZ00449
      Location:491 → 727
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:892 → 1081
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:876 → 900
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:432 → 493
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:386 → 422
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:842 → 880
      F-box-like
      pfam17811
      Location:103 → 138
      JHD; Jumonji helical domain
      cd21785
      Location:278 → 344
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:1 → 104
      cupin_RmlC-like; RmlC-like cupin superfamily

    9. XM_036014590.1 → XP_035870483.1  lysine-specific demethylase 2B isoform X7

      UniProtKB/TrEMBL
      A0A7E6CUD3, A0A833YW16
      Conserved Domains (9) summary
      PTZ00449
      Location:491 → 727
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:892 → 1081
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:876 → 900
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:432 → 493
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:386 → 422
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:842 → 880
      F-box-like
      pfam17811
      Location:103 → 138
      JHD; Jumonji helical domain
      cd21785
      Location:278 → 344
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:1 → 104
      cupin_RmlC-like; RmlC-like cupin superfamily
    Nucleotide Protein
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