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    TLR8 toll like receptor 8 [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

    Gene ID: 117026860, updated on 30-Mar-2024

    Summary

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    Gene symbol
    TLR8
    Gene description
    toll like receptor 8
    See related
    EnsemblRapid:ENSRFEG00010025043
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rhinolophus ferrumequinum
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
    Orthologs
    human mouse all
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    Genomic context

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    See TLR8 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) X NC_046284.1 (117084897..117124920, complement)

    Chromosome X - NC_046284.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC117027198 Neighboring gene thymosin beta 4 X-linked Neighboring gene toll like receptor 7 Neighboring gene phosphoribosyl pyrophosphate synthetase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_046284.1 Chromosome X Reference mRhiFer1_v1.p

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pattern recognition receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of interleukin-6 production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in toll-like receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    toll-like receptor 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mRhiFer1_v1.p

    Genomic

    1. NC_046284.1 Reference mRhiFer1_v1.p

      Range
      117084897..117124920 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033114241.1 → XP_032970132.1  toll-like receptor 8

      UniProtKB/TrEMBL
      A0A671FHF0, A0A7J8AXE6
      Conserved Domains (5) summary
      TIGR00864
      Location:740 → 823
      PCC; polycystin cation channel protein
      smart00255
      Location:878 → 1014
      TIR; Toll - interleukin 1 - resistance
      PLN00113
      Location:59 → 616
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:62 → 85
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:637 → 698
      LRR_8; Leucine rich repeat

    2. XM_033114155.1 → XP_032970046.1  toll-like receptor 8

      UniProtKB/TrEMBL
      A0A671FHF0, A0A7J8AXE6
      Conserved Domains (5) summary
      TIGR00864
      Location:740 → 823
      PCC; polycystin cation channel protein
      smart00255
      Location:878 → 1014
      TIR; Toll - interleukin 1 - resistance
      PLN00113
      Location:59 → 616
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:62 → 85
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:637 → 698
      LRR_8; Leucine rich repeat

    3. XM_033114066.1 → XP_032969957.1  toll-like receptor 8

      UniProtKB/TrEMBL
      A0A671FHF0, A0A7J8AXE6
      Related
      ENSRFEP00010050629.1, ENSRFET00010059820.1
      Conserved Domains (5) summary
      TIGR00864
      Location:740 → 823
      PCC; polycystin cation channel protein
      smart00255
      Location:878 → 1014
      TIR; Toll - interleukin 1 - resistance
      PLN00113
      Location:59 → 616
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:62 → 85
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:637 → 698
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version

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