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    TLR8 toll like receptor 8 [ Myotis myotis ]

    Gene ID: 118654527, updated on 30-Mar-2024

    Summary

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    Gene symbol
    TLR8
    Gene description
    toll like receptor 8
    Locus tag
    mMyoMyo1_019173
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Myotis myotis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
    Orthologs
    human mouse all
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    Genomic context

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    See TLR8 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    100 current mMyoMyo1.p (GCF_014108235.1) Unplaced Scaffold NW_023416346.1 (127589661..127605449, complement)

    NW_023416346.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene thymosin beta 4 X-linked Neighboring gene U1 spliceosomal RNA Neighboring gene toll like receptor 7 Neighboring gene phosphoribosyl pyrophosphate synthetase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023416346 Unplaced Scaffold Reference mMyoMyo1.p Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pattern recognition receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of interleukin-6 production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in toll-like receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    toll-like receptor 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Myotis myotis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mMyoMyo1.p Primary Assembly

    Genomic

    1. NW_023416346.1 Reference mMyoMyo1.p Primary Assembly

      Range
      127589661..127605449 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036305893.1 → XP_036161786.1  toll-like receptor 8

      UniProtKB/TrEMBL
      A0A1B2RXC8, A0A7J7YG62
      Conserved Domains (5) summary
      PRK15370
      Location:30 → 233
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      TIGR00864
      Location:740 → 823
      PCC; polycystin cation channel protein
      smart00255
      Location:878 → 1014
      TIR; Toll - interleukin 1 - resistance
      PLN00113
      Location:164 → 737
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:64 → 87
      LRR_RI; leucine-rich repeat [structural motif]

    2. XM_036305894.1 → XP_036161787.1  toll-like receptor 8

      UniProtKB/TrEMBL
      A0A1B2RXC8, A0A7J7YG62
      Conserved Domains (5) summary
      PRK15370
      Location:30 → 233
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      TIGR00864
      Location:740 → 823
      PCC; polycystin cation channel protein
      smart00255
      Location:878 → 1014
      TIR; Toll - interleukin 1 - resistance
      PLN00113
      Location:164 → 737
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:64 → 87
      LRR_RI; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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