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    KDM2B lysine demethylase 2B [ Myotis myotis ]

    Gene ID: 118678173, updated on 30-Mar-2024

    Summary

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    Gene symbol
    KDM2B
    Gene description
    lysine demethylase 2B
    Locus tag
    mMyoMyo1_007236
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Myotis myotis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
    Orthologs
    human mouse all
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    Genomic context

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    See KDM2B in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    100 current mMyoMyo1.p (GCF_014108235.1) Unplaced Scaffold NW_023416325.1 (14815141..14905655)

    NW_023416325.1Genomic Context describing neighboring genes Neighboring gene ORAI calcium release-activated calcium modulator 1 Neighboring gene U6 spliceosomal RNA Neighboring gene ring finger protein 34 Neighboring gene U1 spliceosomal RNA Neighboring gene anaphase promoting complex subunit 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023416325 Unplaced Scaffold Reference mMyoMyo1.p Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone demethylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein demethylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lysine-specific demethylase 2B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Myotis myotis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mMyoMyo1.p Primary Assembly

    Genomic

    1. NW_023416325.1 Reference mMyoMyo1.p Primary Assembly

      Range
      14815141..14905655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036353443.1 → XP_036209336.1  lysine-specific demethylase 2B isoform X1

      Conserved Domains (10) summary
      PTZ00449
      Location:708 → 953
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1125 → 1335
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:151 → 226
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1130 → 1154
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:631 → 692
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:585 → 621
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1096 → 1134
      F-box-like
      pfam17811
      Location:303 → 338
      JHD; Jumonji helical domain
      cd21785
      Location:477 → 543
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:198 → 304
      cupin_RmlC-like; RmlC-like cupin superfamily

    2. XM_036353449.1 → XP_036209342.1  lysine-specific demethylase 2B isoform X6

      Conserved Domains (9) summary
      cd09293
      Location:1050 → 1260
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:151 → 226
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      PHA03307
      Location:615 → 800
      PHA03307; transcriptional regulator ICP4; Provisional
      sd00034
      Location:1055 → 1079
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:556 → 617
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam12937
      Location:1021 → 1059
      F-box-like
      pfam17811
      Location:303 → 338
      JHD; Jumonji helical domain
      cd21785
      Location:477 → 543
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:198 → 304
      cupin_RmlC-like; RmlC-like cupin superfamily

    3. XM_036353445.1 → XP_036209338.1  lysine-specific demethylase 2B isoform X3

      Conserved Domains (10) summary
      PTZ00449
      Location:690 → 898
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1070 → 1280
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:151 → 226
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1075 → 1099
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:631 → 692
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:585 → 621
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1041 → 1079
      F-box-like
      pfam17811
      Location:303 → 338
      JHD; Jumonji helical domain
      cd21785
      Location:477 → 543
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:198 → 304
      cupin_RmlC-like; RmlC-like cupin superfamily

    4. XM_036353446.1 → XP_036209339.1  lysine-specific demethylase 2B isoform X4

      UniProtKB/TrEMBL
      A0A7J7S1U5
      Conserved Domains (10) summary
      PTZ00449
      Location:690 → 895
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1067 → 1277
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:151 → 226
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1072 → 1096
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:631 → 692
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:585 → 621
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1038 → 1076
      F-box-like
      pfam17811
      Location:303 → 338
      JHD; Jumonji helical domain
      cd21785
      Location:477 → 543
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:198 → 304
      cupin_RmlC-like; RmlC-like cupin superfamily

    5. XM_036353444.1 → XP_036209337.1  lysine-specific demethylase 2B isoform X2

      Conserved Domains (10) summary
      PTZ00449
      Location:702 → 947
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1119 → 1329
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:145 → 220
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1124 → 1148
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:625 → 686
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:579 → 615
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1090 → 1128
      F-box-like
      pfam17811
      Location:297 → 332
      JHD; Jumonji helical domain
      cd21785
      Location:471 → 537
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:192 → 298
      cupin_RmlC-like; RmlC-like cupin superfamily

    6. XM_036353448.1 → XP_036209341.1  lysine-specific demethylase 2B isoform X5

      UniProtKB/TrEMBL
      A0A7J7S1S8
      Conserved Domains (10) summary
      PTZ00449
      Location:684 → 889
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:1061 → 1271
      AMN1; Antagonist of mitotic exit network protein 1
      smart00558
      Location:145 → 220
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00034
      Location:1066 → 1090
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:625 → 686
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:579 → 615
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:1032 → 1070
      F-box-like
      pfam17811
      Location:297 → 332
      JHD; Jumonji helical domain
      cd21785
      Location:471 → 537
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:192 → 298
      cupin_RmlC-like; RmlC-like cupin superfamily

    7. XM_036353450.1 → XP_036209343.1  lysine-specific demethylase 2B isoform X7

      Conserved Domains (9) summary
      PTZ00449
      Location:508 → 753
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd09293
      Location:925 → 1135
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:930 → 954
      LRR_AMN1; leucine-rich repeat [structural motif]
      cd15644
      Location:431 → 492
      PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
      pfam02008
      Location:385 → 421
      zf-CXXC; CXXC zinc finger domain
      pfam12937
      Location:896 → 934
      F-box-like
      pfam17811
      Location:103 → 138
      JHD; Jumonji helical domain
      cd21785
      Location:277 → 343
      CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
      cl40423
      Location:1 → 104
      cupin_RmlC-like; RmlC-like cupin superfamily
    Nucleotide Protein
    Heading Accession and Version

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