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    ARHGEF40 Rho guanine nucleotide exchange factor 40 [ Myotis myotis ]

    Gene ID: 118679658, updated on 30-Mar-2024

    Summary

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    Gene symbol
    ARHGEF40
    Gene description
    Rho guanine nucleotide exchange factor 40
    Locus tag
    mMyoMyo1_000953
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Myotis myotis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGEF40 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    100 current mMyoMyo1.p (GCF_014108235.1) Unplaced Scaffold NW_023416313.1 (149889597..149911956, complement)

    NW_023416313.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein SA-like Neighboring gene transmembrane protein 253 Neighboring gene zinc finger protein 219 Neighboring gene uncharacterized LOC118648985 Neighboring gene U6 spliceosomal RNA Neighboring gene ribonuclease A family member 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023416313 Unplaced Scaffold Reference mMyoMyo1.p Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho guanine nucleotide exchange factor 40

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Myotis myotis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mMyoMyo1.p Primary Assembly

    Genomic

    1. NW_023416313.1 Reference mMyoMyo1.p Primary Assembly

      Range
      149889597..149911956 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036295546.1 → XP_036151439.1  rho guanine nucleotide exchange factor 40 isoform X5

      UniProtKB/TrEMBL
      A0A7J8AHW9
      Conserved Domains (3) summary
      cd13242
      Location:1254 → 1389
      PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
      cl02488
      Location:786 → 980
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl02571
      Location:1096 → 1255
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    2. XM_036295554.1 → XP_036151447.1  rho guanine nucleotide exchange factor 40 isoform X6

      UniProtKB/TrEMBL
      A0A7J8AHW9
      Conserved Domains (3) summary
      cd13242
      Location:1281 → 1416
      PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
      cl02488
      Location:813 → 1007
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl02571
      Location:1123 → 1282
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    3. XM_036295560.1 → XP_036151453.1  rho guanine nucleotide exchange factor 40 isoform X7

      UniProtKB/TrEMBL
      A0A7J8AHW9
      Conserved Domains (3) summary
      cd13242
      Location:1272 → 1407
      PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
      cl02488
      Location:812 → 998
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl02571
      Location:1114 → 1273
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    4. XM_036295535.1 → XP_036151428.1  rho guanine nucleotide exchange factor 40 isoform X3

      UniProtKB/TrEMBL
      A0A7J8AHW9
      Conserved Domains (3) summary
      cd13242
      Location:1272 → 1407
      PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
      cl02488
      Location:812 → 998
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl02571
      Location:1114 → 1273
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    5. XM_036356677.1 → XP_036212570.1  rho guanine nucleotide exchange factor 40 isoform X2

      UniProtKB/TrEMBL
      A0A7J8AHW9
      Conserved Domains (3) summary
      cd13242
      Location:1281 → 1416
      PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
      cl02488
      Location:813 → 1007
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl02571
      Location:1123 → 1282
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    6. XM_036356669.1 → XP_036212562.1  rho guanine nucleotide exchange factor 40 isoform X1

      UniProtKB/TrEMBL
      A0A7J8AHW9
      Conserved Domains (3) summary
      cd13242
      Location:1281 → 1416
      PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
      cl02488
      Location:813 → 1007
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl02571
      Location:1123 → 1282
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    7. XM_036295539.1 → XP_036151432.1  rho guanine nucleotide exchange factor 40 isoform X4

      UniProtKB/TrEMBL
      A0A7J8AHW9
      Conserved Domains (3) summary
      cd13242
      Location:1272 → 1407
      PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
      cl02488
      Location:812 → 998
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl02571
      Location:1114 → 1273
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    Nucleotide Protein
    Heading Accession and Version

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