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    LOC121290931 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [ Carcharodon carcharias (great white shark) ]

    Gene ID: 121290931, updated on 12-Sep-2024

    Summary

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    Gene symbol
    LOC121290931
    Gene description
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
    See related
    EnsemblRapid:ENSCHSG00020007077
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Carcharodon carcharias
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Elasmobranchii; Galeomorphii; Galeoidea; Lamniformes; Alopiidae; Carcharodon
    Orthologs
    zebrafish all
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    Genomic context

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    See LOC121290931 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    100 current sCarCar2.pri (GCF_017639515.1) 2 NC_054468.1 (113599352..114402049)

    Chromosome 2 - NC_054468.1Genomic Context describing neighboring genes Neighboring gene hydroxyacid oxidase (glycolate oxidase) 1 Neighboring gene thioredoxin-related transmembrane protein 4 Neighboring gene U6 spliceosomal RNA Neighboring gene phospholipase C, beta 4a

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_054468.1 Chromosome 2 Reference sCarCar2.pri Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in memory IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Carcharodon carcharias Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference sCarCar2.pri Primary Assembly

    Genomic

    1. NC_054468.1 Reference sCarCar2.pri Primary Assembly

      Range
      113599352..114402049
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041211986.1 → XP_041067920.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1

      Related
      ENSCHSP00020012325.1, ENSCHST00020013714.1
      Conserved Domains (5) summary
      cd00275
      Location:720 → 839
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08591
      Location:316 → 686
      PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
      cd13361
      Location:22 → 149
      PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
      cd16208
      Location:155 → 304
      EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
      pfam17380
      Location:951 → 1182
      DUF5401; Family of unknown function (DUF5401)

    2. XM_041211997.1 → XP_041067931.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2

      Related
      ENSCHSP00020012295.1, ENSCHST00020013682.1
      Conserved Domains (5) summary
      cd00275
      Location:720 → 839
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08591
      Location:316 → 686
      PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
      cd13361
      Location:22 → 149
      PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
      cd16208
      Location:155 → 304
      EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
      pfam17380
      Location:951 → 1182
      DUF5401; Family of unknown function (DUF5401)

    3. XM_041212003.1 → XP_041067937.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X3

      Related
      ENSCHSP00020012164.1, ENSCHST00020013529.1
      Conserved Domains (5) summary
      cd00275
      Location:618 → 737
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08591
      Location:214 → 584
      PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
      cd16208
      Location:53 → 202
      EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
      pfam17380
      Location:849 → 1080
      DUF5401; Family of unknown function (DUF5401)
      cl17171
      Location:1 → 47
      PH-like; Pleckstrin homology-like domain

    RNA

    1. XR_005945906.1 RNA Sequence

      Related
      ENSCHST00020013649.1

    2. XR_005945910.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version