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    LATS2 large tumor suppressor kinase 2 [ Vulpes lagopus (Arctic fox) ]

    Gene ID: 121497072, updated on 22-Mar-2024

    Summary

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    Gene symbol
    LATS2
    Gene description
    large tumor suppressor kinase 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Vulpes lagopus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
    Orthologs
    human mouse all
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    Genomic context

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    See LATS2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    100 current ASM1834538v1 (GCF_018345385.1) 8 NC_054831.1 (34052887..34126683, complement)

    Chromosome 8 - NC_054831.1Genomic Context describing neighboring genes Neighboring gene EEF1A lysine methyltransferase 1 Neighboring gene exportin 4 Neighboring gene cytoskeleton-associated protein 2-like Neighboring gene Sin3A associated protein 18

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_054831.1 Chromosome 8 Reference ASM1834538v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hippo signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of organ growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase LATS2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Vulpes lagopus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1834538v1 Primary Assembly

    Genomic

    1. NC_054831.1 Reference ASM1834538v1 Primary Assembly

      Range
      34052887..34126683 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041766118.1 → XP_041622052.1  serine/threonine-protein kinase LATS2

      Conserved Domains (2) summary
      cd05626
      Location:663 → 1043
      STKc_LATS2; Catalytic domain of the Protein Serine/Threonine Kinase, Large Tumor Suppressor 2
      cd14398
      Location:101 → 141
      UBA_LATS2; UBA domain found in vertebrate serine/threonine-protein kinase LATS2
    Nucleotide Protein Strain
    Heading Accession and Version

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