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    KMT2C lysine methyltransferase 2C [ Dromiciops gliroides (monito del monte) ]

    Gene ID: 122728347, updated on 22-Mar-2024

    Summary

    Gene symbol
    KMT2C
    Gene description
    lysine methyltransferase 2C
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Dromiciops gliroides
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Microbiotheria; Microbiotheriidae; Dromiciops
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See KMT2C in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    61
    Annotation release Status Assembly Chr Location
    100 current mDroGli1.pri (GCF_019393635.1) 5 NC_057865.1 (91179221..91451415)

    Chromosome 5 - NC_057865.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC122729578 Neighboring gene chaperonin containing TCP1 subunit 8 like 2 Neighboring gene 60S ribosomal protein L11-like Neighboring gene U6 spliceosomal RNA Neighboring gene polypeptide N-acetylgalactosaminyltransferase 11-like Neighboring gene polypeptide N-acetylgalactosaminyltransferase 11-like Neighboring gene pancreatic progenitor cell differentiation and proliferation factor-like

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_057865.1 Chromosome 5 Reference mDroGli1.pri

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3K4 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of MLL3/4 complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    histone-lysine N-methyltransferase 2C

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Dromiciops gliroides Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mDroGli1.pri

    Genomic

    1. NC_057865.1 Reference mDroGli1.pri

      Range
      91179221..91451415
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_043966872.1XP_043822807.1  histone-lysine N-methyltransferase 2C isoform X1

      Conserved Domains (17) summary
      smart00541
      Location:46324675
      FYRN; FY-rich domain, N-terminal region
      smart00398
      Location:16831736
      HMG; high mobility group
      PHA03247
      Location:20392546
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:27092944
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:11001122
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:349394
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:474524
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10251071
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:396441
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9681024
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:11021152
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:253336
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44734577
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam06070
      Location:17342217
      Herpes_UL32; Herpesvirus large structural phosphoprotein UL32
      pfam09606
      Location:31383411
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19171
      Location:48294981
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl02651
      Location:46824768
      FYRC; F/Y rich C-terminus
    2. XM_043966877.1XP_043822812.1  histone-lysine N-methyltransferase 2C isoform X6

      Conserved Domains (17) summary
      smart00541
      Location:46324675
      FYRN; FY-rich domain, N-terminal region
      smart00398
      Location:16831736
      HMG; high mobility group
      PHA03247
      Location:20392546
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:27092944
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:11001122
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:349394
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:474524
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10251071
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:396441
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9681024
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:11021152
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:253336
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44734577
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam06070
      Location:17342217
      Herpes_UL32; Herpesvirus large structural phosphoprotein UL32
      pfam09606
      Location:31383411
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19171
      Location:48254977
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl02651
      Location:46824768
      FYRC; F/Y rich C-terminus
    3. XM_043966874.1XP_043822809.1  histone-lysine N-methyltransferase 2C isoform X3

      Conserved Domains (17) summary
      smart00541
      Location:46314674
      FYRN; FY-rich domain, N-terminal region
      smart00398
      Location:16831736
      HMG; high mobility group
      PHA03247
      Location:20392546
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:27092944
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:11001122
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:349394
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:474524
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10251071
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:396441
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9681024
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:11021152
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:253336
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44724576
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam06070
      Location:17342217
      Herpes_UL32; Herpesvirus large structural phosphoprotein UL32
      pfam09606
      Location:31383411
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19171
      Location:48284980
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl02651
      Location:46814767
      FYRC; F/Y rich C-terminus
    4. XM_043966875.1XP_043822810.1  histone-lysine N-methyltransferase 2C isoform X4

      Conserved Domains (17) summary
      smart00541
      Location:46314674
      FYRN; FY-rich domain, N-terminal region
      smart00398
      Location:16831736
      HMG; high mobility group
      PHA03247
      Location:20392546
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:27092944
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:11001122
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:349394
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:474524
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10251071
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:396441
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9681024
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:11021152
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:253336
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44724576
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam06070
      Location:17342217
      Herpes_UL32; Herpesvirus large structural phosphoprotein UL32
      pfam09606
      Location:31383411
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19171
      Location:48284980
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl02651
      Location:46814767
      FYRC; F/Y rich C-terminus
    5. XM_043966878.1XP_043822813.1  histone-lysine N-methyltransferase 2C isoform X7

      Conserved Domains (17) summary
      smart00541
      Location:46164659
      FYRN; FY-rich domain, N-terminal region
      smart00398
      Location:16671720
      HMG; high mobility group
      PHA03247
      Location:20232530
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26932928
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:11001122
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:349394
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:474524
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10251071
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:396441
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9681024
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:11021152
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:253336
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44574561
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam06070
      Location:17182201
      Herpes_UL32; Herpesvirus large structural phosphoprotein UL32
      pfam09606
      Location:31223395
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19171
      Location:48134965
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl02651
      Location:46664752
      FYRC; F/Y rich C-terminus
    6. XM_043966880.1XP_043822815.1  histone-lysine N-methyltransferase 2C isoform X8

      Conserved Domains (17) summary
      smart00541
      Location:46154658
      FYRN; FY-rich domain, N-terminal region
      smart00398
      Location:16671720
      HMG; high mobility group
      PHA03247
      Location:20232530
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26932928
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:11001122
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:349394
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:474524
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10251071
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:396441
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9681024
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:11021152
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:253336
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44564560
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam06070
      Location:17182201
      Herpes_UL32; Herpesvirus large structural phosphoprotein UL32
      pfam09606
      Location:31223395
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19171
      Location:48124964
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl02651
      Location:46654751
      FYRC; F/Y rich C-terminus
    7. XM_043966876.1XP_043822811.1  histone-lysine N-methyltransferase 2C isoform X5

      Conserved Domains (17) summary
      smart00541
      Location:46314674
      FYRN; FY-rich domain, N-terminal region
      smart00398
      Location:16821735
      HMG; high mobility group
      PHA03247
      Location:20382545
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:27082943
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:11001122
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:349394
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:474524
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10251071
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:396441
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9681024
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:11021152
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:253336
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44724576
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam06070
      Location:17332216
      Herpes_UL32; Herpesvirus large structural phosphoprotein UL32
      pfam09606
      Location:31373410
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19171
      Location:48284980
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl02651
      Location:46814767
      FYRC; F/Y rich C-terminus
    8. XM_043966881.1XP_043822816.1  histone-lysine N-methyltransferase 2C isoform X9

      Conserved Domains (17) summary
      smart00541
      Location:45924635
      FYRN; FY-rich domain, N-terminal region
      smart00398
      Location:16431696
      HMG; high mobility group
      PHA03247
      Location:19992506
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26692904
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10601082
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:349394
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:474524
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:9851031
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:396441
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:928984
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10621112
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:253336
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44334537
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam06070
      Location:16942177
      Herpes_UL32; Herpesvirus large structural phosphoprotein UL32
      pfam09606
      Location:30983371
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19171
      Location:47894941
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl02651
      Location:46424728
      FYRC; F/Y rich C-terminus
    9. XM_043966873.1XP_043822808.1  histone-lysine N-methyltransferase 2C isoform X2

      Conserved Domains (17) summary
      smart00541
      Location:46314674
      FYRN; FY-rich domain, N-terminal region
      smart00398
      Location:16821735
      HMG; high mobility group
      PHA03247
      Location:20382545
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:27082943
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10991121
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:349394
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:474524
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10241070
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:396441
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9671023
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:11011151
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:253336
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44724576
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam06070
      Location:17332216
      Herpes_UL32; Herpesvirus large structural phosphoprotein UL32
      pfam09606
      Location:31373410
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19171
      Location:48284980
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      cl02651
      Location:46814767
      FYRC; F/Y rich C-terminus