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    Epn1 epsin 1 [ Mus musculus (house mouse) ]

    Gene ID: 13854, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Epn1provided by MGI
    Official Full Name
    epsin 1provided by MGI
    Primary source
    MGI:MGI:1333763
    See related
    Ensembl:ENSMUSG00000035203 AllianceGenome:MGI:1333763
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ibp1
    Summary
    Predicted to enable several functions, including clathrin adaptor activity; clathrin binding activity; and transmembrane transporter binding activity. Acts upstream of or within several processes, including Notch signaling pathway; female pregnancy; and in utero embryonic development. Predicted to be located in cytosol; postsynaptic membrane; and presynaptic membrane. Predicted to be part of clathrin vesicle coat. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; endosome; and postsynapse. Is expressed in embryo. Orthologous to human EPN1 (epsin 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in duodenum adult (RPKM 208.8), colon adult (RPKM 120.0) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Epn1 in Genome Data Viewer
    Location:
    7 A1; 7 2.94 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (5083207..5101178)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (5080137..5098179)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 15510 Neighboring gene coiled-coil domain containing 106 Neighboring gene STARR-positive B cell enhancer ABC_E3697 Neighboring gene STARR-positive B cell enhancer ABC_E9020 Neighboring gene STARR-positive B cell enhancer ABC_E4891 Neighboring gene U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 Neighboring gene STARR-positive B cell enhancer ABC_E4892 Neighboring gene ret finger protein-like 4 Neighboring gene RAS-like, family 2, locus 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development. Song K, et al. J Clin Invest, 2021 Jan 4. PMID 32960814, Free PMC Article
    2. Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling. Dong Y, et al. Cells, 2021 Jul 29. PMID 34440686, Free PMC Article
    3. Epsin-mediated degradation of IP3R1 fuels atherosclerosis. Dong Y, et al. Nat Commun, 2020 Aug 7. PMID 32770009, Free PMC Article
    4. Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency. Tessneer KL, et al. Arterioscler Thromb Vasc Biol, 2014 Feb. PMID 24311377, Free PMC Article
    5. The interaction of epsin and Eps15 with the clathrin adaptor AP-2 is inhibited by mitotic phosphorylation and enhanced by stimulation-dependent dephosphorylation in nerve terminals. Chen H, et al. J Biol Chem, 1999 Feb 5. PMID 9920862

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling.
      Title: Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling.
    2. Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development.
      Title: Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development.
    3. Epsin-mediated degradation of IP3R1 fuels atherosclerosis.
      Title: Epsin-mediated degradation of IP3R1 fuels atherosclerosis.
    4. Diabetes attenuated VEGF-C-induced lymphangiogenesis in corneal micropocket and Matrigel plug assays in WT mice but not in mice with inducible lymphatic-specific deficiency of epsins 1 and 2 (LEC-iDKO).
      Title: Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes.
    5. Epsins are required for Dishevelled stability and Wnt signalling activation in colon cancer development.
      Title: Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.
    6. epsins 1 and 2 have a critical role in the temporal and spatial regulation of VEGFR3 abundance and signaling in collecting lymphatic trunks during lymphatic valve formation
      Title: Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.
    7. Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.
      Title: Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.
    8. Epsins function specifically to downregulate VEGFR2 by mediating activated VEGFR2 internalization and degradation and that genetic reduction of VEGFR2 level protects against excessive angiogenesis caused by epsin loss.
      Title: Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.
    9. Data indicate a Cbl/p85/epsin-1 pathway in erythropoietin receptor (EpoR) endocytosis.
      Title: Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis.
    10. Loss of epsins 1 and 2 impaired endocytosis and degradation of VEGFR2, resulting in excessive VEGF signaling and compromised tumor vascular function.
      Title: Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.
    Submit: New GeneRIF Correction See all GeneRIFs (12)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (3)  1 citation

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC106041

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables clathrin adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables clathrin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular sequestering activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular sequestering activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within Notch signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in clathrin coat assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within embryonic organ development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in endocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within female pregnancy IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within in utero embryonic development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in membrane fission ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of sprouting angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of sprouting angiogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of clathrin coat assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Schaffer collateral - CA1 synapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of clathrin vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in clathrin-coated pit IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in postsynapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in postsynapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in presynapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in presynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    epsin-1
    Names
    EPS-15-interacting protein 1
    intersectin-EH-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001252454.2 → NP_001239383.1  epsin-1 isoform 1

      See identical proteins and their annotated locations for NP_001239383.1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      Consensus CDS
      CCDS20758.1
      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1
      Related
      ENSMUSP00000043340.7, ENSMUST00000045277.7
      Conserved Domains (2) summary
      PRK07764
      Location:270 → 437
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd16990
      Location:19 → 142
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    2. NM_001372500.1 → NP_001359429.1  epsin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162893
      Consensus CDS
      CCDS90155.1
      Conserved Domains (3) summary
      PHA03247
      Location:256 → 524
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:267 → 393
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd16990
      Location:19 → 142
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    3. NM_001412337.1 → NP_001399266.1  epsin-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1

    4. NM_001412338.1 → NP_001399267.1  epsin-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1

    5. NM_001412339.1 → NP_001399268.1  epsin-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1

    6. NM_001412340.1 → NP_001399269.1  epsin-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1

    7. NM_001412341.1 → NP_001399270.1  epsin-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1

    8. NM_001412342.1 → NP_001399271.1  epsin-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1

    9. NM_001412343.1 → NP_001399272.1  epsin-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1

    10. NM_001412344.1 → NP_001399273.1  epsin-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1

    11. NM_001412345.1 → NP_001399274.1  epsin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162893

    12. NM_001412346.1 → NP_001399275.1  epsin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162893

    13. NM_001412347.1 → NP_001399276.1  epsin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162893

    14. NM_001412348.1 → NP_001399277.1  epsin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162893

    15. NM_001412349.1 → NP_001399278.1  epsin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162893

    16. NM_001412350.1 → NP_001399279.1  epsin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162893
      Related
      ENSMUSP00000146638.2, ENSMUST00000208634.2

    17. NM_001412351.1 → NP_001399280.1  epsin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162893

    18. NM_001412352.1 → NP_001399281.1  epsin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162893

    19. NM_001412353.1 → NP_001399282.1  epsin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162893

    20. NM_001412354.1 → NP_001399283.1  epsin-1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC162893

    21. NM_001412355.1 → NP_001399284.1  epsin-1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC162893

    22. NM_001412356.1 → NP_001399285.1  epsin-1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC162893

    23. NM_001412357.1 → NP_001399286.1  epsin-1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC162893

    24. NM_001412358.1 → NP_001399287.1  epsin-1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC162893

    25. NM_001412359.1 → NP_001399288.1  epsin-1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC162893

    26. NM_001412360.1 → NP_001399289.1  epsin-1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC162893

    27. NM_001412361.1 → NP_001399290.1  epsin-1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC162893

    28. NM_001412362.1 → NP_001399291.1  epsin-1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC162893

    29. NM_001412363.1 → NP_001399292.1  epsin-1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC162893

    30. NM_001412364.1 → NP_001399293.1  epsin-1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC162893

    31. NM_001412365.1 → NP_001399294.1  epsin-1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC162893

    32. NM_001412366.1 → NP_001399295.1  epsin-1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC162893

    33. NM_001412367.1 → NP_001399296.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    34. NM_001412368.1 → NP_001399297.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    35. NM_001412369.1 → NP_001399298.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    36. NM_001412370.1 → NP_001399299.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    37. NM_001412371.1 → NP_001399300.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    38. NM_001412372.1 → NP_001399301.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    39. NM_001412373.1 → NP_001399302.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    40. NM_001412374.1 → NP_001399303.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    41. NM_001412375.1 → NP_001399304.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    42. NM_001412376.1 → NP_001399305.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    43. NM_001412377.1 → NP_001399306.1  epsin-1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC162893

    44. NM_001412378.1 → NP_001399307.1  epsin-1 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC162893

    45. NM_001412379.1 → NP_001399308.1  epsin-1 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC162893

    46. NM_001412380.1 → NP_001399309.1  epsin-1 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC162893

    47. NM_001412381.1 → NP_001399310.1  epsin-1 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC162893

    48. NM_001412382.1 → NP_001399311.1  epsin-1 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC162893

    49. NM_001412383.1 → NP_001399312.1  epsin-1 isoform 20

      Status: VALIDATED

      Source sequence(s)
      AC162893

    50. NM_001412384.1 → NP_001399313.1  epsin-1 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC162893

    51. NM_001412385.1 → NP_001399314.1  epsin-1 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC162893

    52. NM_001412386.1 → NP_001399315.1  epsin-1 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC162893

    53. NM_001412388.1 → NP_001399317.1  epsin-1 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC162893

    54. NM_001412389.1 → NP_001399318.1  epsin-1 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC162893

    55. NM_001412390.1 → NP_001399319.1  epsin-1 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC162893

    56. NM_001412391.1 → NP_001399320.1  epsin-1 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC162893

    57. NM_001412392.1 → NP_001399321.1  epsin-1 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC162893

    58. NM_001412393.1 → NP_001399322.1  epsin-1 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC162893

    59. NM_001412394.1 → NP_001399323.1  epsin-1 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC162893

    60. NM_001412395.1 → NP_001399324.1  epsin-1 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC162893

    61. NM_001412397.1 → NP_001399326.1  epsin-1 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC162893

    62. NM_001412398.1 → NP_001399327.1  epsin-1 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC162893

    63. NM_001412399.1 → NP_001399328.1  epsin-1 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC162893

    64. NM_001412400.1 → NP_001399329.1  epsin-1 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC162893

    65. NM_001412401.1 → NP_001399330.1  epsin-1 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC162893

    66. NM_001412402.1 → NP_001399331.1  epsin-1 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC162893

    67. NM_001412403.1 → NP_001399332.1  epsin-1 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC162893

    68. NM_010147.5 → NP_034277.1  epsin-1 isoform 1

      See identical proteins and their annotated locations for NP_034277.1

      Status: VALIDATED

      Source sequence(s)
      AC162893
      Consensus CDS
      CCDS20758.1
      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1
      Related
      ENSMUSP00000096445.4, ENSMUST00000098845.10
      Conserved Domains (2) summary
      PRK07764
      Location:270 → 437
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd16990
      Location:19 → 142
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      5083207..5101178
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539531.4 → XP_006539594.2  epsin-1 isoform X1

      See identical proteins and their annotated locations for XP_006539594.2

      UniProtKB/Swiss-Prot
      Q80VP1
      Conserved Domains (3) summary
      PHA03247
      Location:256 → 524
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:267 → 393
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd16990
      Location:19 → 142
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    2. XM_030242119.1 → XP_030097979.1  epsin-1 isoform X11

      Conserved Domains (2) summary
      PHA03247
      Location:63 → 333
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:74 → 200
      PRK07764; DNA polymerase III subunits gamma and tau; Validated

    3. XM_036152660.1 → XP_036008553.1  epsin-1 isoform X1

      Conserved Domains (3) summary
      PHA03247
      Location:256 → 524
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:267 → 393
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd16990
      Location:19 → 142
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    4. XM_036152661.1 → XP_036008554.1  epsin-1 isoform X6

      UniProtKB/Swiss-Prot
      O70446, Q6NX78, Q80VP1
      Conserved Domains (2) summary
      PRK07764
      Location:270 → 437
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd16990
      Location:19 → 142
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80VP1.3 GenPept UniProtKB/Swiss-Prot:Q80VP1

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