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    C17C3.1 Acyl-coenzyme A thioesterase 8;palmitoyl-CoA hydrolase [ Caenorhabditis elegans ]

    Gene ID: 173942, updated on 2-Nov-2024

    Summary

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    Official Symbol
    C17C3.1
    Official Full Name
    Acyl-coenzyme A thioesterase 8;palmitoyl-CoA hydrolase
    Primary source
    WormBase:WBGene00015887
    Locus tag
    CELE_C17C3.1
    See related
    AllianceGenome:WB:WBGene00015887
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid catabolic process. Predicted to be located in membrane. Predicted to be active in peroxisomal matrix. Orthologous to human ACOT8 (acyl-CoA thioesterase 8). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See C17C3.1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (5570572..5575006)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene NR LBD domain-containing protein Neighboring gene pseudo Neighboring gene SPK domain-containing protein Neighboring gene tRNA-Val Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables fatty acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fatty acyl-CoA hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in acyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fatty acid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in peroxisomal matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Acyl-coenzyme A thioesterase 8;palmitoyl-CoA hydrolase
    NP_001040743.1
    • Confirmed by transcript evidence
    NP_001367517.1
    • Partially confirmed by transcript evidence
    NP_495075.1
    • Confirmed by transcript evidence
    NP_495077.1
    • Confirmed by transcript evidence
    NP_495079.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5570572..5575006
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062676.5 → NP_495077.1  Acyl-coenzyme A thioesterase 8 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495077.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KYT8

    2. NM_062674.7 → NP_495075.1  palmitoyl-CoA hydrolase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495075.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BIA9
      Conserved Domains (3) summary
      cd03444
      Location:243 → 347
      Thioesterase_II_repeat1; Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP) ...
      cd03445
      Location:63 → 157
      Thioesterase_II_repeat2; Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP) ...
      TIGR00189
      Location:58 → 348
      tesB; acyl-CoA thioesterase II

    3. NM_001381419.1 → NP_001367517.1  Acyl-coenzyme A thioesterase 8 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KYT7

    4. NM_062678.5 → NP_495079.1  palmitoyl-CoA hydrolase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495079.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KYT6
      Conserved Domains (3) summary
      cd03444
      Location:232 → 336
      Thioesterase_II_repeat1; Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP) ...
      cd03445
      Location:52 → 146
      Thioesterase_II_repeat2; Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP) ...
      TIGR00189
      Location:47 → 337
      tesB; acyl-CoA thioesterase II

    5. NM_001047278.5 → NP_001040743.1  palmitoyl-CoA hydrolase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040743.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B0M0L9
      Conserved Domains (3) summary
      cd03444
      Location:212 → 316
      Thioesterase_II_repeat1; Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP) ...
      cd03445
      Location:32 → 126
      Thioesterase_II_repeat2; Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP) ...
      TIGR00189
      Location:27 → 317
      tesB; acyl-CoA thioesterase II
    Nucleotide Protein
    Heading Accession and Version

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