Sprr2i small proline-rich protein 2I [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Sprr2iprovided by MGI
Official Full Name: small proline-rich protein 2Iprovided by MGI
Primary source: MGI:MGI:1330309
See related: Ensembl:ENSMUSG00000042157 AllianceGenome:MGI:1330309
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable lipid binding activity. Predicted to be a structural constituent of skin epidermis. Predicted to be involved in keratinization. Predicted to be located in cornified envelope and cytoplasm. Predicted to be active in extracellular region and secretory granule. Orthologous to several human genes including SPRR2A (small proline rich protein 2A); SPRR2B (small proline rich protein 2B); and SPRR2D (small proline rich protein 2D). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward stomach adult (RPKM 25.4) See more
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 3 F1; 3 40.14 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (92315298..92316577)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (92407991..92409271)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables lipid binding	ISO Inferred from Sequence Orthology more info
enables structural constituent of skin epidermis	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in epidermis development	NAS Non-traceable Author Statement more info	PubMed
involved_in keratinization	IEA Inferred from Electronic Annotation more info
involved_in keratinocyte differentiation	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in cornified envelope	ISO Inferred from Sequence Orthology more info
located_in cornified envelope	NAS Non-traceable Author Statement more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in extracellular region	ISO Inferred from Sequence Orthology more info
is_active_in secretory granule	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: small proline-rich protein 2I

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.