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    srb11 cyclin CycC-like Srb mediator subunit Srb11 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539651, updated on 18-Sep-2024

    Summary

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    Official Symbol
    srb11
    Official Full Name
    cyclin CycC-like Srb mediator subunit Srb11
    Primary source
    PomBase:SPBC12D12.06
    Locus tag
    SPOM_SPBC12D12.06
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See srb11 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (2316055..2317654)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene calcium-binding subfamily carrier protein Neighboring gene DNA polymerase zeta Rev7 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene thioredoxin Trx2 Neighboring gene tRNA-Pro

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of the mediator subunit cyclin C and its implications for CDK8 function. Hoeppner S, et al. J Mol Biol, 2005 Jul 29. PMID 15979093
    2. Cyclin C influences the timing of mitosis in fission yeast. Banyai G, et al. Mol Biol Cell, 2017 Jul 1. PMID 28515143, Free PMC Article
    3. TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution. Samuelsen CO, et al. Proc Natl Acad Sci U S A, 2003 May 27. PMID 12738880, Free PMC Article
    4. Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe. Spåhr H, et al. J Biol Chem, 2000 Jan 14. PMID 10625684
    5. Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. Rallis C, et al. Biol Open, 2014 Feb 15. PMID 24463365, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription coactivator activity IC
    Inferred by Curator
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cyclin CycC-like Srb mediator subunit Srb11

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2316055..2317654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021862.3 → NP_595953.1  cyclin CycC-like Srb mediator subunit Srb11 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595953.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94503
      Conserved Domains (3) summary
      COG5333
      Location:1 → 228
      CCL1; Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit [Cell division and chromosome partitioning / Transcription / DNA replication, recombination, and repair]
      cd00043
      Location:32 → 125
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
      cl00050
      Location:137 → 189
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
    Nucleotide Protein
    Heading Accession and Version

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