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    nrm1 protein nrm1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539737, updated on 18-Sep-2024

    Summary

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    Official Symbol
    nrm1
    Official Full Name
    protein nrm1
    Primary source
    PomBase:SPBC16A3.07c
    Locus tag
    SPOM_SPBC16A3.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See nrm1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (4285944..4288583)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Hrd1 ubiquitin ligase complex subunit Ufd1 Neighboring gene ncRNA Neighboring gene protein stm1 Neighboring gene ncRNA Neighboring gene tRNA specific adenosine deaminase Neighboring gene ncRNA Neighboring gene nucleoporin Rae1 Neighboring gene ncRNA Neighboring gene mitochondrial 37S ribosomal protein mS23

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell Cycle-Regulated Transcription of CENP-A by the MBF Complex Ensures Optimal Level of CENP-A for Centromere Formation. Aristizabal-Corrales D, et al. Genetics, 2019 Mar. PMID 30635289, Free PMC Article
    2. Phosphorylation of the MBF repressor Yox1p by the DNA replication checkpoint keeps the G1/S cell-cycle transcriptional program active. Caetano C, et al. PLoS One, 2011 Feb 16. PMID 21359180, Free PMC Article
    3. The fission yeast homeodomain protein Yox1p binds to MBF and confines MBF-dependent cell-cycle transcription to G1-S via negative feedback. Aligianni S, et al. PLoS Genet, 2009 Aug. PMID 19714215, Free PMC Article
    4. DNA replication checkpoint promotes G1-S transcription by inactivating the MBF repressor Nrm1. de Bruin RA, et al. Proc Natl Acad Sci U S A, 2008 Aug 12. PMID 18682565, Free PMC Article
    5. Two fission yeast high mobility group box proteins in the maintenance of genomic integrity following doxorubicin insult. Tang MY, et al. Gene, 2015 May 10. PMID 25701403

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription corepressor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MBF transcription complex EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    protein nrm1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4285944..4288583
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023803.3 → NP_596782.1  protein nrm1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596782.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O42913
      Conserved Domains (1) summary
      pfam08528
      Location:136 → 160
      Whi5; Whi5 like
    Nucleotide Protein
    Heading Accession and Version

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