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    kae1 EKC/KEOPS complex N(6)-L-threonylcarbamoyladenine synthase subunit [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540141, updated on 18-Sep-2024

    Summary

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    Official Symbol
    kae1
    Official Full Name
    EKC/KEOPS complex N(6)-L-threonylcarbamoyladenine synthase subunit
    Primary source
    PomBase:SPBC16D10.03
    Locus tag
    SPOM_SPBC16D10.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    pgp2
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    Genomic context

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    See kae1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (3590963..3592684)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA (guanine-N2-)-methyltransferase catalytic subunit Trm11 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA replication endonuclease-helicase Dna2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Negative Regulation of the Mis17-Mis6 Centromere Complex by mRNA Decay Pathway and EKC/KEOPS Complex in Schizosaccharomyces pombe. Xu X, et al. G3 (Bethesda), 2019 Jun 5. PMID 30967422, Free PMC Article
    2. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    3. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    4. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
    5. The mitochondrial genome of the fission yeast Schizosaccharomyces pombe: highly homologous introns are inserted at the same position of the otherwise less conserved cox1 genes in Schizosaccharomyces pombe and Aspergillus nidulans. Lang BF. EMBO J, 1984 Sep. PMID 6092057, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables N(6)-L-threonylcarbamoyladenine synthase activity ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA threonylcarbamoyladenosine modification ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of EKC/KEOPS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    EKC/KEOPS complex N(6)-L-threonylcarbamoyladenine synthase subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3590963..3592684
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022419.3 → NP_596498.1  EKC/KEOPS complex N(6)-L-threonylcarbamoyladenine synthase subunit [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596498.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94637
      Conserved Domains (2) summary
      PTZ00340
      Location:5 → 346
      PTZ00340; O-sialoglycoprotein endopeptidase-like protein; Provisional
      cl22532
      Location:8 → 116
      Carbam_trans_N; Carbamoyltransferase N-terminus
    Nucleotide Protein
    Heading Accession and Version

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