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    Tcl1b1 T cell leukemia/lymphoma 1B, 1 [ Mus musculus (house mouse) ]

    Gene ID: 27379, updated on 28-Oct-2024

    Summary

    Official Symbol
    Tcl1b1provided by MGI
    Official Full Name
    T cell leukemia/lymphoma 1B, 1provided by MGI
    Primary source
    MGI:MGI:1351601
    See related
    Ensembl:ENSMUSG00000066359 AllianceGenome:MGI:1351601
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable protein kinase binding activity and protein serine/threonine kinase activator activity. Predicted to be involved in intracellular signal transduction. Orthologous to human TCL1B (TCL1 family AKT coactivator B). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Restricted expression toward ovary adult (RPKM 3.0) See more
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    Genomic context

    See Tcl1b1 in Genome Data Viewer
    Location:
    12 E; 12 55.21 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (105125963..105132884)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (105159704..105166625)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32062 Neighboring gene T cell leukemia/lymphoma 1B, 2 Neighboring gene T cell leukemia/lymphoma 1B, 5 Neighboring gene T cell leukemia/lymphoma 1B, 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein serine/threonine kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular signal transduction ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013773.2NP_038801.1  protein TCL1B1

      See identical proteins and their annotated locations for NP_038801.1

      Status: PROVISIONAL

      Source sequence(s)
      AC124777
      Consensus CDS
      CCDS36545.1
      UniProtKB/Swiss-Prot
      P56840
      UniProtKB/TrEMBL
      Q3UWQ4
      Related
      ENSMUSP00000082118.6, ENSMUST00000085043.7
      Conserved Domains (1) summary
      pfam01840
      Location:1114
      TCL1_MTCP1; TCL1/MTCP1 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      105125963..105132884
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)