LIF LIF interleukin 6 family cytokine [Bos taurus (cattle)] - Gene

Summary

Official Symbol: LIFprovided by VGNC
Official Full Name: LIF interleukin 6 family cytokineprovided by VGNC
Primary source: VGNC:VGNC:30880
See related: BGD:BT16756; Ensembl:ENSBTAG00000007424
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 17

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	17	NC_037344.1 (69262879..69267183, complement)

Chromosome 17 - NC_037344.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LIF regulates the expression of miR-27a-3p and HOXA10 in bovine endometrial epithelial cells via STAT3 pathway.
Title: LIF regulates the expression of miR-27a-3p and HOXA10 in bovine endometrial epithelial cells via STAT3 pathway.
Studied the effects of leukemia inhibitory factor (LIF) on bovine oocyte maturation and early embryo development in vitro.
Title: Leukemia inhibitory factor enhances bovine oocyte maturation and early embryo development.
results suggest that leukemia inhibitory factor and macrophage-colony stimulating factor are produced in the endometrium and may play different roles in early and mid-pregnancy
Title: Gene expression of leukemia inhibitory factor (LIF) and macrophage colony stimulating factor (M-CSF) in bovine endometrium during early pregnancy.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

LIF1 (e-PCR)
- UniSTS:253701

LIF2 (e-PCR)
- UniSTS:253702

LIF (e-PCR), detects polymorphism
- UniSTS:279665

LIF (e-PCR), detects polymorphism
- UniSTS:278649

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed
enables leukemia inhibitory factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: leukemia inhibitory factor

Names: bLIF; cholinergic differentiation factor; leukemia inhibitory factor (cholinergic differentiation factor)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.