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    Pamr1 peptidase domain containing associated with muscle regeneration 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311252, updated on 2-Nov-2024

    Summary

    Official Symbol
    Pamr1provided by RGD
    Official Full Name
    peptidase domain containing associated with muscle regeneration 1provided by RGD
    Primary source
    RGD:1308745
    See related
    EnsemblRapid:ENSRNOG00000005348 AllianceGenome:RGD:1308745
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ramp; RGD1308745
    Summary
    Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Orthologous to human PAMR1 (peptidase domain containing associated with muscle regeneration 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Uterus (RPKM 151.0), Kidney (RPKM 150.9) and 5 other tissues See more
    Orthologs
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    Genomic context

    See Pamr1 in Genome Data Viewer
    Location:
    3q32
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (109340411..109443595)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (88889061..88988615)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (92403533..92502094)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 44 Neighboring gene uncharacterized LOC108350422 Neighboring gene four-jointed box kinase 1 Neighboring gene solute carrier family 1 member 2 Neighboring gene CD44 molecule

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    inactive serine protease PAMR1
    Names
    regeneration associated muscle protease

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107755.3NP_001101225.2  inactive serine protease PAMR1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6HNP0, D4A0A3
      Related
      ENSRNOP00000059877.3, ENSRNOT00000064282.4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      109340411..109443595
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063283704.1XP_063139774.1  inactive serine protease PAMR1 isoform X1

      Related
      ENSRNOP00000098929.1, ENSRNOT00000125020.1