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    SRAE_1000254800 E3 ubiquitin-protein ligase UBR5 [ Strongyloides ratti ]

    Gene ID: 36376658, updated on 25-Jan-2024

    Summary

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    Gene symbol
    SRAE_1000254800
    Gene description
    E3 ubiquitin-protein ligase UBR5
    Locus tag
    SRAE_1000254800
    Gene type
    protein coding
    RNA name
    E3 ubiquitin-protein ligase UBR5
    RefSeq status
    PROVISIONAL
    Organism
    Strongyloides ratti (strain: ED321 Heterogonic)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Panagrolaimoidea; Strongyloididae; Strongyloides
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    Genomic context

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    See SRAE_1000254800 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_037307.1 (8188093..8196520)

    Chromosome 1 - NC_037307.1Genomic Context describing neighboring genes Neighboring gene Hypothetical protein Neighboring gene Putative GTP-binding protein 6 Neighboring gene Hypothetical protein Neighboring gene EB domain and Cysteine-rich repeat-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037307.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase UBR5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037307.1 Reference assembly

      Range
      8188093..8196520
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024649637.1 → XP_024503494.1  E3 ubiquitin-protein ligase UBR5 [Strongyloides ratti]

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A090L859
      Conserved Domains (4) summary
      smart00396
      Location:992 → 1052
      ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
      pfam11547
      Location:155 → 205
      E3_UbLigase_EDD; E3 ubiquitin ligase EDD
      pfam00658
      Location:2305 → 2356
      PABP; Poly-adenylate binding protein, unique domain
      cl27008
      Location:2409 → 2704
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    Nucleotide Protein
    Heading Accession and Version

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