LMX1B LIM homeobox transcription factor 1 beta [Gallus gallus (chicken)] - Gene

Summary

Symbol: LMX1Bprovided by CGNC
Full Name: LIM homeobox transcription factor 1 betaprovided by CGNC
Primary source: CGNC:621
See related: Ensembl:ENSGALG00010028911
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: LMX; LMX1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	17	NC_052548.1 (10665426..10802338)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	17	NC_052589.1 (10076023..10212937)

Chromosome 17 - NC_052548.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Myogenic precursors in limb bud were devoid of Lmx1b expression. Lmx1b is not only expressed at early stages of limb development but maintains its pattern, at least until after birth. New details of Lmx1b expression on cellular basis within limb.
Title: Characterization of migration behavior of myogenic precursor cells in the limb bud with respect to Lmx1b expression.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in neuron differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LIM/homeobox protein LMX-1.2

Names: LIM homeobox protein; LIM/homeobox protein 1; homeobox protein LMX-1; homeodomain protein (lmx)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205358.2 → NP_990689.2 LIM/homeobox protein LMX-1.2

See identical proteins and their annotated locations for NP_990689.2

Status: VALIDATED

Source sequence(s)

JAENSK010000308

UniProtKB/Swiss-Prot

P53413

UniProtKB/TrEMBL

A0A8V1AM41

Related

ENSGALP00010043070.1, ENSGALT00010069944.1

Conserved Domains (3) summary

cd09371
Location:56 → 108

LIM1_Lmx1b; The first LIM domain of Lmx1b

cd09378
Location:115 → 169

LIM2_Lmx1a_Lmx1b; The second LIM domain of Lmx1a and Lmx1b

pfam00046
Location:221 → 275

Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

10665426..10802338

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046901667.1 → XP_046757623.1 LIM/homeobox protein LMX-1.2 isoform X1

UniProtKB/TrEMBL

A0A8V1AKC6

Related

ENSGALP00010043072.1, ENSGALT00010069946.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

10076023..10212937

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046928764.1 → XP_046784720.1 LIM/homeobox protein LMX-1.2 isoform X1

UniProtKB/TrEMBL

A0A8V1AKC6
XM_046928765.1 → XP_046784721.1 LIM/homeobox protein LMX-1.2 isoform X2