CYP3A4 cytochrome P450 family 3 subfamily A member 4 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: CYP3A4provided by VGNC
Official Full Name: cytochrome P450 family 3 subfamily A member 4provided by VGNC
Primary source: VGNC:VGNC:13644
Locus tag: CK820_G0047467
See related: Ensembl:ENSPTRG00000033773
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
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Genomic context

Location:: chromosome: 6

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	6	NC_072404.2 (109228920..109255915, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	7	NC_072405.1 (105575720..105602682, complement)

Chromosome 6 - NC_072404.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

CYP3A4_2210 (e-PCR)
- UniSTS:280639

CYPNOA (e-PCR)
- UniSTS:36431

D7S2832 (e-PCR)
- UniSTS:78468

D7S2874 (e-PCR)
- UniSTS:27061

SHGC-16521 (e-PCR)
- UniSTS:1733

RH68186 (e-PCR)
- UniSTS:2009

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IEA Inferred from Electronic Annotation more info	PubMed
enables testosterone 6-beta-hydroxylase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in oxidative demethylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in steroid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cytochrome P450 family 3 subfamily A member 4

Names: cytochrome P450, family 3, subfamily A, polypeptide 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001122775.1 → NP_001116247.1 cytochrome P450 family 3 subfamily A member 4

See identical proteins and their annotated locations for NP_001116247.1

Status: PROVISIONAL

Source sequence(s)

EF589797

UniProtKB/TrEMBL

A0A2I3SYU7, A0A2J8Q0F2, A0A6D2XJ66, B1NL93

Related

ENSPTRP00000045445.5, ENSPTRT00000049146.6

Conserved Domains (1) summary

pfam00067
Location:39 → 493

p450; Cytochrome P450

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

109228920..109255915 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)