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    Rmnd1 required for meiotic nuclear division 1 homolog [ Mus musculus (house mouse) ]

    Gene ID: 66084, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Rmnd1provided by MGI
    Official Full Name
    required for meiotic nuclear division 1 homologprovided by MGI
    Primary source
    MGI:MGI:1913334
    See related
    Ensembl:ENSMUSG00000019763 AllianceGenome:MGI:1913334
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610042C05Rik
    Summary
    Predicted to be involved in positive regulation of mitochondrial translation. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 11. Orthologous to human RMND1 (required for meiotic nuclear division 1 homolog). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 26.5), kidney adult (RPKM 13.6) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rmnd1 in Genome Data Viewer
    Location:
    10 A1; 10 2.06 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (4353168..4382583, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (4403169..4432405, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_25640 Neighboring gene A kinase anchor protein 12 Neighboring gene predicted gene, 40592 Neighboring gene STARR-seq mESC enhancer starr_25637 Neighboring gene STARR-positive B cell enhancer ABC_E11428 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5999414-5999597 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5988889-5989072 Neighboring gene STARR-seq mESC enhancer starr_25630 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5958087-5958270 Neighboring gene zinc finger and BTB domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E2315 Neighboring gene acidic residue methyltransferase 1 Neighboring gene STARR-seq mESC enhancer starr_25628 Neighboring gene coiled-coil domain containing 170 Neighboring gene predicted gene, 22739 Neighboring gene STARR-seq mESC enhancer starr_25624 Neighboring gene glutathione S-transferase, pi 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of mitochondrial translation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of mitochondrial translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    required for meiotic nuclear division protein 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358796.2 → NP_001345725.1  required for meiotic nuclear division protein 1 homolog isoform a

      Status: VALIDATED

      Source sequence(s)
      AC133902
      Consensus CDS
      CCDS56675.1
      UniProtKB/Swiss-Prot
      Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
      Conserved Domains (1) summary
      pfam02582
      Location:227 → 404
      DUF155; Uncharacterized ACR, YagE family COG1723

    2. NM_001429326.1 → NP_001416255.1  required for meiotic nuclear division protein 1 homolog isoform a

      Status: VALIDATED

      Source sequence(s)
      AC133902
      UniProtKB/Swiss-Prot
      Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0

    3. NM_001429327.1 → NP_001416256.1  required for meiotic nuclear division protein 1 homolog isoform a

      Status: VALIDATED

      Source sequence(s)
      AC133902
      UniProtKB/Swiss-Prot
      Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0

    4. NM_001429328.1 → NP_001416257.1  required for meiotic nuclear division protein 1 homolog isoform a

      Status: VALIDATED

      Source sequence(s)
      AC133902
      UniProtKB/Swiss-Prot
      Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0

    5. NM_001429329.1 → NP_001416258.1  required for meiotic nuclear division protein 1 homolog isoform a

      Status: VALIDATED

      Source sequence(s)
      AC133902
      UniProtKB/Swiss-Prot
      Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0

    6. NM_001429330.1 → NP_001416259.1  required for meiotic nuclear division protein 1 homolog isoform b

      Status: VALIDATED

      Source sequence(s)
      AC133902

    7. NM_001429331.1 → NP_001416260.1  required for meiotic nuclear division protein 1 homolog isoform c

      Status: VALIDATED

      Source sequence(s)
      AC133902

    8. NM_001429332.1 → NP_001416261.1  required for meiotic nuclear division protein 1 homolog isoform c

      Status: VALIDATED

      Source sequence(s)
      AC133902

    9. NM_025343.7 → NP_079619.4  required for meiotic nuclear division protein 1 homolog isoform a

      See identical proteins and their annotated locations for NP_079619.4

      Status: VALIDATED

      Source sequence(s)
      AC133902
      Consensus CDS
      CCDS56675.1
      UniProtKB/Swiss-Prot
      Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
      Related
      ENSMUSP00000043355.5, ENSMUST00000042251.11
      Conserved Domains (1) summary
      pfam02582
      Location:227 → 404
      DUF155; Uncharacterized ACR, YagE family COG1723

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      4353168..4382583 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512478.5 → XP_006512541.1  required for meiotic nuclear division protein 1 homolog isoform X1

      Conserved Domains (1) summary
      pfam02582
      Location:227 → 404
      DUF155; Uncharacterized ACR, YagE family COG1723

    2. XM_036155948.1 → XP_036011841.1  required for meiotic nuclear division protein 1 homolog isoform X3

      Conserved Domains (1) summary
      pfam02582
      Location:15 → 192
      DUF155; Uncharacterized ACR, YagE family COG1723

    3. XM_036155947.1 → XP_036011840.1  required for meiotic nuclear division protein 1 homolog isoform X3

      Conserved Domains (1) summary
      pfam02582
      Location:15 → 192
      DUF155; Uncharacterized ACR, YagE family COG1723

    4. XM_017314053.3 → XP_017169542.1  required for meiotic nuclear division protein 1 homolog isoform X1

      Conserved Domains (1) summary
      pfam02582
      Location:227 → 404
      DUF155; Uncharacterized ACR, YagE family COG1723

    5. XM_036155945.1 → XP_036011838.1  required for meiotic nuclear division protein 1 homolog isoform X1

      UniProtKB/Swiss-Prot
      Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
      Conserved Domains (1) summary
      pfam02582
      Location:227 → 404
      DUF155; Uncharacterized ACR, YagE family COG1723

    6. XM_006512477.5 → XP_006512540.1  required for meiotic nuclear division protein 1 homolog isoform X1

      Conserved Domains (1) summary
      pfam02582
      Location:227 → 404
      DUF155; Uncharacterized ACR, YagE family COG1723

    7. XM_036155944.1 → XP_036011837.1  required for meiotic nuclear division protein 1 homolog isoform X1

      UniProtKB/Swiss-Prot
      Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
      Conserved Domains (1) summary
      pfam02582
      Location:227 → 404
      DUF155; Uncharacterized ACR, YagE family COG1723

    8. XM_036155952.1 → XP_036011845.1  required for meiotic nuclear division protein 1 homolog isoform X4

      Conserved Domains (1) summary
      pfam02582
      Location:6 → 160
      DUF155; Uncharacterized ACR, YagE family COG1723

    9. XM_036155951.1 → XP_036011844.1  required for meiotic nuclear division protein 1 homolog isoform X4

      Conserved Domains (1) summary
      pfam02582
      Location:6 → 160
      DUF155; Uncharacterized ACR, YagE family COG1723

    10. XM_036155950.1 → XP_036011843.1  required for meiotic nuclear division protein 1 homolog isoform X4

      Conserved Domains (1) summary
      pfam02582
      Location:6 → 160
      DUF155; Uncharacterized ACR, YagE family COG1723

    11. XM_036155949.1 → XP_036011842.1  required for meiotic nuclear division protein 1 homolog isoform X4

      Conserved Domains (1) summary
      pfam02582
      Location:6 → 160
      DUF155; Uncharacterized ACR, YagE family COG1723

    12. XM_017314054.3 → XP_017169543.1  required for meiotic nuclear division protein 1 homolog isoform X1

      Conserved Domains (1) summary
      pfam02582
      Location:227 → 404
      DUF155; Uncharacterized ACR, YagE family COG1723

    13. XM_036155943.1 → XP_036011836.1  required for meiotic nuclear division protein 1 homolog isoform X1

      UniProtKB/Swiss-Prot
      Q3TQK1, Q8BW19, Q8CI78, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
      Conserved Domains (1) summary
      pfam02582
      Location:227 → 404
      DUF155; Uncharacterized ACR, YagE family COG1723

    14. XM_036155946.1 → XP_036011839.1  required for meiotic nuclear division protein 1 homolog isoform X2

    RNA

    1. XR_004936244.1 RNA Sequence

    2. XR_004936243.1 RNA Sequence

    3. XR_004936245.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CI78.1 GenPept UniProtKB/Swiss-Prot:Q8CI78

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