U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    BRDT bromodomain testis associated [ Homo sapiens (human) ]

    Gene ID: 676, updated on 2-Nov-2024

    Summary

    Official Symbol
    BRDTprovided by HGNC
    Official Full Name
    bromodomain testis associatedprovided by HGNC
    Primary source
    HGNC:HGNC:1105
    See related
    Ensembl:ENSG00000137948 MIM:602144; AllianceGenome:HGNC:1105
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CT9; BRD6; SPGF21
    Summary
    BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
    Expression
    Restricted expression toward testis (RPKM 59.8) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See BRDT in Genome Data Viewer
    Location:
    1p22.1
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (91949371..92014428)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (91794237..91859235)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (92414928..92479985)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene transforming growth factor beta receptor 3 Neighboring gene uncharacterized LOC124904659 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:92251462-92251665 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1307 Neighboring gene Sharpr-MPRA regulatory region 12731 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1308 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1309 Neighboring gene RNA, 7SL, cytoplasmic 653, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:92333973-92334474 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:92334475-92334974 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1310 Neighboring gene H3K27ac-H3K4me1 hESC enhancers GRCh37_chr1:92350516-92351279 and GRCh37_chr1:92351280-92352042 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:92359890-92360390 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:92371721-92372221 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:92376156-92376656 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:92376657-92377157 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:92407032-92407718 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:92407719-92408404 Neighboring gene uncharacterized LOC124904218 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:92495241-92495742 Neighboring gene epoxide hydrolase 4 Neighboring gene lysophosphatidylcholine acyltransferase 2b, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    HIV-1 interactions

    Replication interactions

    Interaction Pubs
    Knockdown of bromodomain, testis-specific (BRDT) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables histone reader activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables lysine-acetylated histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription coactivator activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chromatin remodeling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in male meiosis I ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in male meiotic nuclear division ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within_positive_effect positive regulation of gene expression ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of RNA splicing ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sperm DNA condensation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    bromodomain testis-specific protein
    Names
    RING3-like protein
    bromodomain, testis-specific
    cancer/testis antigen 9

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001242805.2NP_001229734.2  bromodomain testis-specific protein isoform b

      See identical proteins and their annotated locations for NP_001229734.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 4. The resulting isoform (b) lacks a short internal segment compared to isoform a. Variants 1, 2, and 3 all encode the same isoform (b).
      Source sequence(s)
      AC114486, AK302758, AK303008, AY338951, BX648135
      Consensus CDS
      CCDS735.1
      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
      Related
      ENSP00000354568.3, ENST00000362005.7
      Conserved Domains (4) summary
      cd05497
      Location:27133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:272373
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:509571
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:905947
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    2. NM_001242806.2NP_001229735.2  bromodomain testis-specific protein isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) encodes the longest isoform (a).
      Source sequence(s)
      AC114486, AK302758, AK303008, AY338951, BX648135, DB072781
      UniProtKB/Swiss-Prot
      Q58F21
      Conserved Domains (4) summary
      cd05497
      Location:27133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:276377
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:513575
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:909951
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    3. NM_001242807.2NP_001229736.2  bromodomain testis-specific protein isoform c

      See identical proteins and their annotated locations for NP_001229736.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR, lacks an alternate in-frame exon, and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 4. The resulting isoform (c) lacks two internal segments compared to isoform a. Variants 5 and 6 both encode the same protein.
      Source sequence(s)
      AK302758, AK316442, AY338951, BX648135, DC402057
      Consensus CDS
      CCDS55615.1
      UniProtKB/Swiss-Prot
      Q58F21
      Conserved Domains (4) summary
      cd05498
      Location:226327
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:463525
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:859901
      BRD4_CDT; C-terminal domain of bromodomain protein 4
      cl02556
      Location:2787
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    4. NM_001242808.2NP_001229737.2  bromodomain testis-specific protein isoform c

      See identical proteins and their annotated locations for NP_001229737.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) lacks an alternate in-frame exon and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 4. The resulting isoform (c) lacks two internal segments compared to isoform a. Variants 5 and 6 both encode the same protein.
      Source sequence(s)
      AC114486, AK302758, AY338951, BX648135
      Consensus CDS
      CCDS55615.1
      UniProtKB/Swiss-Prot
      Q58F21
      Related
      ENSP00000378038.3, ENST00000394530.7
      Conserved Domains (4) summary
      cd05498
      Location:226327
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:463525
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:859901
      BRD4_CDT; C-terminal domain of bromodomain protein 4
      cl02556
      Location:2787
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    5. NM_001242810.2NP_001229739.2  bromodomain testis-specific protein isoform d

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and coding sequence compared to variant 4. The resulting isoform (d) is shorter at the N-terminus and lacks a short internal segment compared to isoform a.
      Source sequence(s)
      AC114486, AK302758, AY338951, BX648135
      Consensus CDS
      CCDS55616.1
      UniProtKB/Swiss-Prot
      Q58F21
      Related
      ENSP00000359416.2, ENST00000370389.6
      Conserved Domains (4) summary
      cd05498
      Location:199300
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:436498
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:832874
      BRD4_CDT; C-terminal domain of bromodomain protein 4
      cl02556
      Location:160
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    6. NM_001726.4NP_001717.3  bromodomain testis-specific protein isoform b

      See identical proteins and their annotated locations for NP_001717.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 4. The resulting isoform (b) lacks a short internal segment compared to isoform a. Variants 1, 2, and 3 all encode the same isoform (b).
      Source sequence(s)
      AK302758, AY338951, BC047900, BX648135, DC401352
      Consensus CDS
      CCDS735.1
      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
      Related
      ENSP00000384051.1, ENST00000402388.1
      Conserved Domains (4) summary
      cd05497
      Location:27133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:272373
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:509571
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:905947
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    7. NM_207189.4NP_997072.2  bromodomain testis-specific protein isoform b

      See identical proteins and their annotated locations for NP_997072.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 4. The resulting isoform (b) lacks a short internal segment compared to isoform a. Variants 1, 2, and 3 all encode the same isoform (b).
      Source sequence(s)
      AC114486
      Consensus CDS
      CCDS735.1
      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
      Related
      ENSP00000387822.3, ENST00000399546.7
      Conserved Domains (4) summary
      cd05497
      Location:27133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:272373
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:509571
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:905947
      BRD4_CDT; C-terminal domain of bromodomain protein 4

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      91949371..92014428
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006710855.5XP_006710918.1  bromodomain testis-specific protein isoform X1

      See identical proteins and their annotated locations for XP_006710918.1

      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
      Conserved Domains (4) summary
      cd05497
      Location:27133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:272373
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:509571
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:905947
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    2. XM_011542032.4XP_011540334.1  bromodomain testis-specific protein isoform X1

      See identical proteins and their annotated locations for XP_011540334.1

      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
      Conserved Domains (4) summary
      cd05497
      Location:27133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:272373
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:509571
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:905947
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    3. XM_011542034.4XP_011540336.1  bromodomain testis-specific protein isoform X1

      See identical proteins and their annotated locations for XP_011540336.1

      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
      Conserved Domains (4) summary
      cd05497
      Location:27133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:272373
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:509571
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:905947
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    4. XM_047428949.1XP_047284905.1  bromodomain testis-specific protein isoform X1

      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
    5. XM_006710856.5XP_006710919.1  bromodomain testis-specific protein isoform X1

      See identical proteins and their annotated locations for XP_006710919.1

      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
      Conserved Domains (4) summary
      cd05497
      Location:27133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:272373
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:509571
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:905947
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    6. XM_011542035.4XP_011540337.1  bromodomain testis-specific protein isoform X1

      See identical proteins and their annotated locations for XP_011540337.1

      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
      Conserved Domains (4) summary
      cd05497
      Location:27133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:272373
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:509571
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:905947
      BRD4_CDT; C-terminal domain of bromodomain protein 4
    7. XM_047428955.1XP_047284911.1  bromodomain testis-specific protein isoform X1

      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
    8. XM_047428967.1XP_047284923.1  bromodomain testis-specific protein isoform X1

      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
    9. XM_011542036.4XP_011540338.1  bromodomain testis-specific protein isoform X1

      See identical proteins and their annotated locations for XP_011540338.1

      UniProtKB/Swiss-Prot
      A6NF68, B7Z811, B7Z890, B7ZAX7, D3DT32, O14789, Q05DQ4, Q58F21, Q6P5T1, Q7Z4A6, Q8IWI6
      Conserved Domains (4) summary
      cd05497
      Location:27133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:272373
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:509571
      BET; Bromodomain extra-terminal - transcription regulation
      pfam17105
      Location:905947
      BRD4_CDT; C-terminal domain of bromodomain protein 4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      91794237..91859235
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054338477.1XP_054194452.1  bromodomain testis-specific protein isoform X1

    2. XM_054338479.1XP_054194454.1  bromodomain testis-specific protein isoform X1

    3. XM_054338484.1XP_054194459.1  bromodomain testis-specific protein isoform X1

    4. XM_054338481.1XP_054194456.1  bromodomain testis-specific protein isoform X1

    5. XM_054338478.1XP_054194453.1  bromodomain testis-specific protein isoform X1

    6. XM_054338482.1XP_054194457.1  bromodomain testis-specific protein isoform X1

    7. XM_054338483.1XP_054194458.1  bromodomain testis-specific protein isoform X1

    8. XM_054338480.1XP_054194455.1  bromodomain testis-specific protein isoform X1