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    RPS22A ribosomal 40S subunit protein S22A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853249, updated on 3-Nov-2024

    Summary

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    Official Symbol
    RPS22A
    Official Full Name
    ribosomal 40S subunit protein S22A
    Primary source
    SGD:S000003726
    Locus tag
    YJL190C
    See related
    AllianceGenome:SGD:S000003726; FungiDB:YJL190C; VEuPathDB:YJL190C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPS24
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 20. Orthologous to human RPS15A (ribosomal protein S15a). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See RPS22A in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (74910..75302, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Sop4p Neighboring gene ribosomal 40S subunit protein S14B Neighboring gene ribosomal 60S subunit protein L39 Neighboring gene tyrosine protein kinase SWE1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The divergently transcribed genes encoding yeast ribosomal proteins L46 and S24 are activated by shared RPG-boxes. Kraakman LS, et al. Nucleic Acids Res, 1989 Dec 11. PMID 2602141, Free PMC Article
    2. The genes for yeast ribosomal proteins S24 and L46 are adjacent and divergently transcribed. Leer RJ, et al. Nucleic Acids Res, 1985 Feb 11. PMID 4000930, Free PMC Article
    3. Nuclear and nucleolar localization of Saccharomyces cerevisiae ribosomal proteins S22 and S25. Timmers AC, et al. FEBS Lett, 1999 Jun 11. PMID 10386617
    4. Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation. Visweswaraiah J, et al. J Biol Chem, 2012 Nov 2. PMID 22888004, Free PMC Article
    5. Genetic analysis of the ribosome biogenesis factor Ltv1 of Saccharomyces cerevisiae. Merwin JR, et al. Genetics, 2014 Nov. PMID 25213169, Free PMC Article

    See all (91) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S22A
    NP_012345.1
    • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15A and bacterial S8; RPS22A has a paralog, RPS22B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      74910..75302 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181623.1 → NP_012345.1  TPA: ribosomal 40S subunit protein S22A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012345.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VW01, P04648, P0C0W1
      UniProtKB/TrEMBL
      A6ZQE6, B3LPT7, C7GS13, C8ZB29, G2WGI7, N1P8U5
      Conserved Domains (1) summary
      PTZ00158
      Location:1 → 130
      PTZ00158; 40S ribosomal protein S15A; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C0W1.2

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