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    ACTA1 actin alpha 1, skeletal muscle [ Bos taurus (cattle) ]

    Gene ID: 281592, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ACTA1provided by VGNC
    Official Full Name
    actin alpha 1, skeletal muscleprovided by VGNC
    Primary source
    VGNC:VGNC:25573
    See related
    BGD:BT11532; Ensembl:ENSBTAG00000046332
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 28
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (1400446..1403202, complement)

    Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene centriole, cilia and spindle associated protein Neighboring gene small ribosomal subunit protein uS2-like Neighboring gene nucleoporin 133 Neighboring gene sodium/potassium-transporting ATPase subunit beta-3-like Neighboring gene ATP binding cassette subfamily B member 10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Increased body weight via injecting myogenic expression growth hormone-releasing hormone (GHRH) plasmid DNA into sheep. Meng QY, et al. Anim Biotechnol, 2004. PMID 15595702
    2. The nucleotide sequence, structure, and preliminary studies on the transcriptional regulation of the bovine alpha skeletal actin gene. Davey HW, et al. DNA Cell Biol, 1995 Jul. PMID 7626220
    3. The complete amino acid sequence of actins from bovine aorta, bovine heart, bovine fast skeletal muscle, and rabbit slow skeletal muscle. A protein-chemical analysis of muscle actin differentiation. Vandekerckhove J, et al. Differentiation, 1979. PMID 499690
    4. The structure of crystalline profilin-beta-actin. Schutt CE, et al. Nature, 1993 Oct 28. PMID 8413665
    5. Syntenic assignment of human chromosome 1 homologous loci in the bovine. Threadgill DS, et al. Genomics, 1994 Aug. PMID 8001974

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in skeletal muscle thin filament assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in stress fiber IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in striated muscle thin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    actin, alpha skeletal muscle
    Names
    alpha-actin-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174225.1 → NP_776650.1  actin, alpha skeletal muscle

      See identical proteins and their annotated locations for NP_776650.1

      Status: PROVISIONAL

      Source sequence(s)
      U02285
      UniProtKB/TrEMBL
      A4IFM8
      Related
      ENSBTAP00000006534.2, ENSBTAT00000006534.3
      Conserved Domains (2) summary
      smart00268
      Location:7 → 377
      ACTIN; Actin
      cl17037
      Location:4 → 377
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      1400446..1403202 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P68138.1 GenPept UniProtKB/Swiss-Prot:P68138

    Gene LinkOut

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