U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    LOC442497 uncharacterized LOC442497 [ Homo sapiens (human) ]

    Gene ID: 442497, updated on 10-Oct-2023

    Summary

    Go to the top of the page Help
    Gene symbol
    LOC442497
    Gene description
    uncharacterized LOC442497
    See related
    Ensembl:ENSG00000249574
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    7p22.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (379425..382879)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (479911..483365)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (419391..422845)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375118 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17804 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:373151-373812 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:373813-374472 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:376155-376966 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:376967-377776 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:383559-384188 Neighboring gene uncharacterized LOC124901809 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:392059-392793 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:404760-405260 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:405696-405911 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:408996-409520 Neighboring gene MPRA-validated peak6332 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:431351-431892 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:454774-455322 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:460048-460804 Neighboring gene uncharacterized LOC116435278 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:465509-466426 Neighboring gene uncharacterized LOC112267991 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:473022-473858 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:473859-474694 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr7:475441-476640 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:485302-485962 Neighboring gene uncharacterized LOC124901566

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. Maréchal A, et al. Mol Cell, 2014 Jan 23. PMID 24332808, Free PMC Article
    2. Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Li X, et al. Mol Cell Proteomics, 2016 Sep. PMID 27432908, Free PMC Article
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    GeneRIFs: Gene References Into Functions

    Phenotypes

    Go to the top of the page Help

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Clone Names

    • AC226118.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_033960.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK092540
      Related
      ENST00000515213.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      379425..382879
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      479911..483365
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials