show Abstracthide AbstractUnderstanding the alterations AGPs cause on females is critical for developing novel control tools for insect pest species. However in several insect species, such as Mexican fruit fly Anastrepha ludens (Loew) (Diptera: Tephritidae), there is not consistent relationship between food intake, oviposition or remating inhibition. Therefore, we used RNA seq we studied gene expression in mated, virgin and AGP injected females in A. ludens to understand what the potential biological implications are related with mating. We found notorious discrepancy of biological pathways (i.e. mating induced gene expression in pathways associated with immune response, musculature, egg formation and hardening, and chemosensory perception) in AGP injected females compared to mated or virgin females. We report the first transcriptome analysis for A. ludens and discuss our results in terms of the pathways regulated by mating. Thus, further research is necessary, such as proteomic approaches to elucidate the function of AGPs in A. ludens.