show Abstracthide AbstractThis dataset comprises RNA sequencing data from fibroblast cells derived from the skin of 11 avian species following experimental infection with the H5N1 Highly Pathogenic Avian Influenza virus. The cells were isolated from skin of Chicken (Gallus gallus), Rock pigeon (Columba livia), Mountain Hawk-eagle (Nisaetus nipalensis), Northern Goshawk (Accipiter gentilis), Peregrine Falcon (Falco peregrinus), Golden eagle (Aquila chrysaetos), Hooded crane (Grus monacha), White-necked crane (Grus vipio), Japanese crane (Grus japonensis), Okinawa rail (Rallus okinawae), Japanese white stork (Ciconia boyciana).