3NBN,1TTU


Conserved Protein Domain Family
BTD
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pfam09270: BTD (this model, PSSM-Id:286369 is obsolete and has been replaced by 462734)
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Beta-trefoil DNA-binding domain
Members of this family of DNA binding domains adopt a beta-trefoil fold, that is, a capped beta-barrel with internal pseudo threefold symmetry. In the DNA-binding protein LAG-1, it also is the site of mutually exclusive interactions with NotchIC (and the viral protein EBNA2) and co-repressors (SMRT/N-Cor and CIR).
Links
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Statistics
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PSSM-Id: 286369
Aligned: 22 rows
Threshold Bit Score: 189.817
Created: 22-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3NBN_A       158 LCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFFIH-LLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGM 236 human
EUB62193     106 VCIASGTKIALFNRLRSQTVSTRYLHVDAGSFHASSSRWGAFTIH-LLSDDESEAEEFNVRDGYIHYGHTVKLVCSETGM 184 Echinococcus gr...
XP_001600894 167 LCIASGTTVALFNRLRSQTVSTRYLHVNGDQFHASSTQWSTFTIY-LLDDDESENEDFEAKDGYIHYNSTVKLVCKDTGM 245 jewel wasp
XP_002126537 552 LCIPSGSKVSLFNRLRSQTVSTRYLHVTKDGYRASATQWGAFAIH-LIHENQPEANEFEVHDGYVHYGTSVKLVCSVTGY 630 vase tunicate
ABO52982     204 LCISSGSKVSLFNRLRSQTVSTRYLSVQDGAFVASARQWAAFTLH-L-ADGHSSQEDFPPREGYVRYGSLVQLVCTVTGI 281 white-tufted-ea...
KFQ02554     100 LCISSGSKVSLFNRLRSQTVSTRYLSVEGGAFIASARQWAAFTLH-L-ADEHCTRSEFPLREGYIRYGSVVQLVCTATGI 177 white-tailed eagle
XP_005456490 229 LCISSCSRVALFNRLRSQTVSTRYLSVDRGAFIASARHWTAFTIT-MVDDQCADQGGFVLSEGFICYGCVVQLVCTESGA 307 Nile tilapia
CAF93580     148 lcISSCSRVALFNRLRSQTVSTRYLSVDRGAFIVSARQWTAFTITaL-SDHHSGHRD-VLSEGFICDGCVVQLVCTESGV 225 spotted green p...
XP_002662588 200 LCISSGSKVSLFNRLRSQTVSTRYLAVEDGAFVASARQWTAFTVN-LVEETQAVHSEYTMCESYICYGCVVQLVCTDSGV 278 zebrafish
XP_006639825 291 LCISSGSRVSLFNRLRSQTVSTRYLSVEGGAFVASARQWAAFTIT-LGGEQQAEQGQYPPREGYICYGCSVRLVCTGTGV 369 spotted gar

3NBN_A       237 ALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTE----RMYLCLSQERIIQF---------------------QATP 291 human
EUB62193     185 ALPRLIVRKVDKTVVMLDADDPVSQLHKCAFYLKDTD----RMYLCLSQDRIIQH---------------------QAVR 239 Echinococcus gr...
XP_001600894 246 ALPRLIIRKVDKSMASLDADDPVSQLHKCALFLKDTD----HMYLCLSQEKIVPF---------------------NATP 300 jewel wasp
XP_002126537 631 ALPRLIIRKVDRQMASVLSDEPVSQLHKCALYLKDTD----RQYLCLSQEKIIVH---------------------KATQ 685 vase tunicate
ABO52982     282 TLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGSSpgggGTYLCLATEKVVQF---------------------Q--A 338 white-tufted-ea...
KFQ02554     178 TLPPLIIRKVTKQYAMLDVDEPISQLHKCAFQFQGSD----RMYLCLSTEKVIQF---------------------QASP 232 white-tailed eagle
XP_005456490 308 ALPPMVIRKVNKQHAILDVDEPVSQLHKCAFQFRDNP----HAYLCLTNDAIIQY---------------------QAPF 362 Nile tilapia
CAF93580     226 ALPPMVIRKVNKQHAILDVDEPVSQLHKCAFQFRDGP----HAFLCLSNDSVVRHqvrtrplhlgppgppltpgvlQASC 301 spotted green p...
XP_002662588 279 ALPPMVIRKVNKQQACLDVDEPVSQLHKCAFQFRGSD----HMYLCLSNEKIIQF---------------------QASP 333 zebrafish
XP_006639825 370 ALPPMVIRKVNKQHAMLDVNEPVSQLHKCAFQFKDSS----RMYLCLSNEKIIQF---------------------QASP 424 spotted gar

3NBN_A       292 C--PKEPNKEMINDGASW 307 human
EUB62193     240 C--DDNPHRETINDSAAW 255 Echinococcus granulosus
XP_001600894 301 S--PKEANKHMINDGACW 316 jewel wasp
XP_002126537 686 S--TKNPSMDCLSDGACW 701 vase tunicate
ABO52982     339 SpcPKEANRALLndsscw 356 white-tufted-ear marmoset
KFQ02554     233 C--PKEANRELLNDGSCW 248 white-tailed eagle
XP_005456490 363 S--VRDPSKVVLNDGSCW 378 Nile tilapia
CAF93580     302 S--PREPSRVVLNEGSCW 317 spotted green pufferfish
XP_002662588 334 C--PKESNKVSLNDGSCW 349 zebrafish
XP_006639825 425 C--SKDPSKELLNDGSCW 440 spotted gar
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