3K1L


Conserved Protein Domain Family
FANCL_C
?
pfam11793: FANCL_C (this model, PSSM-Id:288626 is obsolete and has been replaced by 463350)
Click on image for an interactive view with Cn3D
FANCL C-terminal domain
This domain is found at the C-terminus of the Fancl protein in humans which is the putative E3 ubiquitin ligase subunit of the FA complex (Fanconi anaemia). Eight subunits of the Fanconi anaemia gene products form a multisubunit nuclear complex which is required for mono-ubiquitination of a downstream FA protein, FANCD2.
Links
?
Statistics
?
PSSM-Id: 288626
Aligned: 10 rows
Threshold Bit Score: 115.983
Created: 13-Jul-2015
Updated: 5-Aug-2015
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
3K1L_A       307 EELRCNICFAYRLd--------GGEVPLVSCDNAKCVLKCHAVCLEEWFKTLMDGKTFLEVSFGQCPFCKAKLSTSFA 376 fruit fly
Q3MUH5       301 FTKDCGICYAYRL---------NGTTPDQVCNEPRCGQPFHQACLYEWLQGLPSSRQSFNVIFGECPYCNKPLTVKSS 369 chicken
Q29B73       302 QEKHCNICFVYRLd--------SGEVPIVSCDNPRCVLQCHAACLEEWFKTLLDGKTFLDVSFGLCPYCKAKLSTSFA 371 Drosophila pseudo...
Q9CR14       303 FSMDCGICYARHL---------NGAIPDQVCNNPQCGQPFHEICLYEWLRGLSTSRQSFNVFFGDCPYCSKPITLKMS 371 house mouse
Q7PSZ3       146 GEDSCGICMNYQDg--------YDRVPVISCDNEQCNLIFHIHCLKEWFATQRESKKIFTISIGNCPYCTHKISSSFD 215 Anopheles gambiae...
Q17FW9       295 DAIQCGICMSYRDd--------QNKIPIISCDNEKCSLIFHIGCLKEWFMSLKDSRTFFAISVGTCPYCKQKVSSSFD 364 yellow fever mosq...
NP_001089161 300 FSMDCGICYAYRLd--------S-AIPDQVCDDPRCGQPFHQACLYEWLRGLPSSRQSFNIIYGECPYCNKPITLKMS 368 African clawed frog
XP_001630199 301 FSMECGICYAYRL---------NDTIPDKACDDPRCGQPFHRDCLYEWLRSLPSSRQSFNMVFGECPYCSKPITVKMT 369 starlet sea anemone
XP_001315697 268 TEIECPICFCERF---------GGELPEIVCENPKCAKHYHRSCLVDWLRENRKMEQSFHCIYGTCPNCGAKIQVDDS 336 Trichomonas vagin...
NP_001032152 221 QQVECGICYAQFLptdeelgarSGTRTDYTCENISCNKSFHSLCLTDWLRSITTTRQSFDVLFGNCPYCSDPVAVKTS 298 thale cress
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap