Conserved Protein Domain Family
Troponin
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pfam00992: Troponin (this model, PSSM-Id:307228 is obsolete and has been replaced by 460018)
Troponin
Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). this Pfam contains members of the TnT subunit. Troponin is a complex of three proteins, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). The troponin complex regulates Ca++ induced muscle contraction. This family includes troponin T and troponin I. Troponin I binds to actin and troponin T binds to tropomyosin.
Links
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Statistics
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PSSM-Id: 307228
Aligned: 105 rows
Threshold Bit Score: 49.4657
Created: 25-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q0D2W2         11 RHHLKSLVLSIAFNLLDAEAKQHIADKESHMSENCPALD-LPGsvQELQDLCKKLHQQIDKVDEERYDMEAKVAKADKEI 89  zebrafish
17_pfamImport   1 KKAERDLCDLQEMINRHFVQRKQEEVELNNLKERIEKRKeMRA--KQLIERQKKEKERQEREKNEKEARERALKEKQEAE 78 
16_pfamImport   1 --IEKDLAELEKLISSHFVKREIDEKEINNLKTKINERIaTRE--EQLKDRQIKLKEREESIALEAKRAEEEIAAAAKKE 76 
18_pfamImport   1 RKVEKDIADLKKLIDQHFVQRKKDEEDLDSLRGRIANRKiVRD--QQIQARNEKLKAREAQLALEKEKREAIENRRKAEE 78 
12_pfamImport   1 KRLEKDLSELKRIIEAHFVQRQKDEVELEELKTRIEKRKeYRE--QQLKQRAERERLRMEAEQLEKDRRAAEEAARKEEE 78 
Q8AVB1        101 KRVEKDFNELQSLINLHFTTRQKEEDELVALKNRIERRRtDRA--DQQRIRTERDRERQARLAEERARREEEAAKLRAEE 178 zebrafish
39_pfamImport   1 RRLEKDFDDLQTLIESHFSARQKEEEELLALRGRIERRRsDRA--EQQRVRAERERERAARLAGERARREEEAAA----N 74 
50_pfamImport   1 KRLEKDYNDLQSLIELHFSSRQKEEEELISLRNRIESRRaDRA--EQQRVRAEQERERQARVAEERSRREEEAAKQRAEE 78 
54_pfamImport   1 KRMEKDMVELQALINAHFEQRKKDEEEIEVLRVRIDERKqKRA--EQIRIRQDRERERMAQEREERKRKEEEEESKRQEE 78 
19_pfamImport   1 KKLEKELQELKKLIDVHFVQRKKDEEELQALENRIEKRKeSRA--AQLAERARREQEKEARLQAEKERREQEAQRRADEE 78 

Q0D2W2         90 EDLKIKVIDLKgK-FKKPALK----------KVRMSADAMLQALLGSKHK-VSMDLRANLKQVK 141 zebrafish
17_pfamImport  79 EARKKELMASM--------AMlnthmdrrrqGKRTTARDAKRKALAERRKpLNIDHLNKEKLME 134
16_pfamImport  77 DDRKKELMLAMsMnFGGYQARmek----mrkGKRATQKEEKKKILSDRRKpLNIDHLSGERLQE 136
18_pfamImport  79 EERKKATMAAI---------QyatsnpkkrlQKKGGNKQEKKKILAARRKnGNIDHLTGPQLAE 133
12_pfamImport  79 ERKKKEAMQALsQsFGGYKAQak-------qRTGRGERERKKKVLAERRKpLNIDHLAVEKLLE 135
Q8AVB1        179 DARKKKILSNKg--YGGFLQKvdq-----kkGKKLTEREKKTKCLLERRKpLNIDHLNQEKLGE 235 zebrafish
39_pfamImport  75 DAKKKKTFTSKs--FGGY-QKadq-----rkSKKLTAREEKKKALTERRRpLNIDHLSQEKLAD 130
50_pfamImport  79 DAKKKMIFSNKs--FGGYLQKvdq-----kkGKKLTAREEKKKALMERRKpLNIDHLNQDKLLE 135
54_pfamImport  79 EARKKAAIANMsLhYGGYLARaek----nkpNKRQTDREKKKKILAERRKpLNIDHLSDDKLRE 138
19_pfamImport  79 AARKKELLHALnAaAHGNQRQdk-------rKGRGTERDKKKKILAERRKqLNIDHLDIEKLKS 135
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