Conserved Protein Domain Family
FXR_C1
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pfam16096: FXR_C1 (this model, PSSM-Id:318344 is obsolete and has been replaced by 465019)
Fragile X-related 1 protein C-terminal region 2
FXR_C1 is a small highly conserved region of the C-terminus of Fragile X-related proteins 1 and 2, FRX1, FRX2. The family is found in association with pfam05641, pfam00013. This family is immediately C-terminal to the core C terminal region, PF12235, and contains at least one block of RGG repeats that bind to G-quartet sequences in a wide variety of mRNAs.
Links
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Statistics
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PSSM-Id: 318344
Aligned: 8 rows
Threshold Bit Score: 87.6307
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_015195769 286 SSTIS-SVLRDPDSNPFSLLD--RAgELDQAGDTDASESQASGDRRRRSRRRRTDQEPSVMDGAAESDGPSVSENGLE 360 spotted gar
XP_012312419 484 KSSIS-SVLKDPDSNPYSLLD--NT-ESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLG 557 Ma's night monkey
XP_011472496 500 YSNNS-GSWDRDNTYSHGALE--TNtETDHTADTDASESLLPANRRRRSRRRRTDEDATMMDGMSESDNASVGENGIV 574 Japanese medaka
XP_003466298 502 nsssissVLKDPDSNPYSLLD--TS-EPEPPVDAEPGEPPPASARRRRSRRRRTDEDRTIMDGGLESDGPSLTENGLE 576 domestic guinea pig
XP_010734905 516 YHNSSaGPRDHEDNHAYGASEvnT--ETDQTADTDASESNVPANRRRRSRRRRTDEDATLMDGMSESDNASMSENGId 591 large yellow croaker
XP_014264021 498 YSNSS-GPRDHEDNHHYGALE--VNtETDQTADTDASDSNLPANRRRRSRRRRTDEDTTLIDGMSESDNASMSENGTv 572 zebra mbuna
AAH55557     486 SNSIS-SVLKDPDGNPYSLLD--NT-ETDQTADTDGSESQMNTSRRRRSRRRRTDEDTTVMDGMSESDNASLSENGLV 559 zebrafish
XP_003229918 493 SSSIS-SVLKDPDSNPYSLLD--NT-ETDQTADTDASESQPVSNRRRRSRRRRTDEDATMMDGALDSDSVSVSENGVE 566 green anole
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