pfam09465: LBR_tudor (this model, PSSM-Id:370513 is obsolete and has been replaced by 462808)
Lamin-B receptor of TUDOR domain
The Lamin-B receptor, found on the TUDOR domain pfam00567, is a chromatin and lamin binding protein in the inner nuclear membrane. It is one of the integral inner Nuclear Envelope membrane proteins responsible for targeting nuclear membranes to chromatin, being a downstream effector of Ran, a small Ras-like nuclear GTPase which regulates NE assembly. Lamin-B receptor interacts with Importin beta, a Ran-binding protein, thereby directly contributing to the fusion of membrane vesicles and the formation of the NE.
Jiyao W et al.(2023). "The conserved domain database in 2023.",