Conserved Protein Domain Family
HMMR_C
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pfam15908: HMMR_C (this model, PSSM-Id:406358 is obsolete and has been replaced by 464934)
Hyaluronan mediated motility receptor C-terminal
HMMR_C is the C-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Links
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Statistics
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PSSM-Id: 406358
Aligned: 7 rows
Threshold Bit Score: 145.808
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_010717202  569 KSEVEKSRK-TIHEDMTSSLkEEIKTWRNLYEELHNKTKPFQQQLDAFEAEKNALLNEQGAAQEELNKLSEAYAKLLGHQ 647  turkey
XP_002935941 1013 QEEEMELLR-KESEKNQQDA-MEANKWRALYEELQNKVRPFQQQLDAFEAEKNALLNENGAAQDELNKLSEAYAKLLGHQ 1090 tropical claw...
XP_007474036  567 QLVMEETRK-TREKN--MEFtEDVKKWRLLYEELYNKTKPFEQQLDAFEAEKRALLNEHGATQEELNKLSESYAKLLGHQ 643  gray short-ta...
O75330        554 QLEDEEGRK-AEKENTTAELtEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQ 632  human
2_pfamImport    3 LLEAEKQRKeAVDENTVIKLrAEAQKWQSLYEELSNKVKPFQEQLDAFEAEKNCLLNENGAAQEELNKLSDAYAKLLGHQ 82  
NP_955874     756 QLAE------ARLQSTSD---SETEHWRNLYEELYAKVKPFQEQLDRFAAERSALLNEKGATQAELNKLADAYANLMGHQ 826  zebrafish
NP_001011731  683 QWEMEEQRQ--DLQRQVDQAqE--KRWEKVR--IY-HLFP-QEQLDAFAAERNALLSENGANQEELNKLSDAYARLLGHQ 754  torafugu

XP_010717202  648 NQKQKIKHVMKLKEDNTHLQQDISKLRALLAKEKQTNKDLQEQLYTIQGIRRFDPSKAFQH--DSKENIPPKTPFKEG 723  turkey
XP_002935941 1091 NQKQKIKHVMKLKIENSELKQEVSKLRAQLAKEKQVEKQLQAHLNEIQGVKRFDPSKAFRH--DVKENVMPKAPLREG 1166 tropical clawed...
XP_007474036  644 NQKQKIKHVMKLKEENNQLKLEVSKLRSQLAKEKQVGKKLQEQINEAKGFKRFDPSKAFQH--ESKENFSPKVPLKEG 719  gray short-tail...
O75330        633 NLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHH--ESKENFALKTPLKEG 708  human
2_pfamImport   83 NQRQKIKHVVKLKEENSQLRQEVTKLRNQLAKEKQVQKKFEDQMKLAQGVRRFDT---FKH--DSKENDVPSTPLREG 155 
NP_955874     827 NQRQKIKHMVKLKEENLELKQEVSKLRSQVGKQKQELDRLKSS----ETTRRFDPSKAFKH--ELKENQKPSSALTQG 898  zebrafish
NP_001011731  755 NQKQKIKHVMKLKDENTSLKQELSKLRSQVSRLKSDQEQLKSMLPGA-PRRRFDPSKAFQHnkENREN-EKNEPLREG 830  torafugu
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