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1AXW:
E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH METHOTREXATE (MTX) AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)
PDB ID:
1AXW
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MMDB ID:
86687
PDB Deposition Date:
1997/10/23
Updated in MMDB:
2010/12
Experimental Method:
x-ray diffraction
Resolution:
1.7 Å
Source Organism:
Escherichia coli
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1AXW: dimeric; determined by author and by software (PISA)
Molecular Components in 1AXW
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Thymidylate Synthase
(Gene symbol:
thyA
)
Chemicals and Non-standard biopolymers (4 molecules)
1
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE
2
2
METHOTREXATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303