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1N8Z:
Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab
PDB ID:
1N8Z
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MMDB ID:
22099
PDB Deposition Date:
2002/11/21
Updated in MMDB:
2018/12
Experimental Method:
x-ray diffraction
Resolution:
2.52 Å
Source Organism:
synthetic construct
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Taxonomy
Molecule
synthetic construct
A, B
Homo sapiens
C
Similar Structures:
VAST+
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Biological Unit for 1N8Z: trimeric; determined by author
Molecular Components in 1N8Z
Label
Count
Molecule
Proteins (3 molecules)
A
1
Herceptin FAB (Antibody) - Light Chain
B
1
Herceptin FAB (Antibody) - Heavy Chain
C
1
Receptor Protein-tyrosine Kinase Erbb-2
Chemicals and Non-standard biopolymers (3 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
SULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303