1O5D: Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)

PDB ID: 1O5DDownload
MMDB ID: 29257
PDB Deposition Date: 2003/9/9
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 1O5D: trimeric; determined by author and by software (PISA)
Molecular Components in 1O5D
Label Count Molecule
Proteins (3 molecules)
1
Coagulation Factor VII
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor VII
(Gene symbol: F7)
Molecule annotation
1
Tissue Factor
(Gene symbol: F3)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZOL-2-YL}-6-[(2-METHYLCYCLOHEXYL)OXY]BENZENOLATE2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZOL-2-YL}-6-[(2-METHYLCYCLOHEXYL)OXY]BENZENOLATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303