1O5F: Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)

PDB ID: 1O5FDownload
MMDB ID: 29259
PDB Deposition Date: 2003/9/9
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.78  Å
Source Organism:
Similar Structures:
Biological Unit for 1O5F: dimeric; determined by author
Molecular Components in 1O5F
Label Count Molecule
Proteins (2 molecules)
1
Serine Protease Hepsin
(Gene symbol: HPN)
Molecule annotation
1
Serine Protease Hepsin
(Gene symbol: HPN)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZOL-2-YL}-6-[(2-METHYLCYCLOHEXYL)OXY]BENZENOLATE2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZOL-2-YL}-6-[(2-METHYLCYCLOHEXYL)OXY]BENZENOLATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303