1O6R: Structures of human oxidosqualene cyclase inhibitors bound to an homologous enzyme

PDB ID: 1O6RDownload
MMDB ID: 24986
PDB Deposition Date: 2002/10/13
Updated in MMDB: 2013/11
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 1O6R: dimeric; determined by author and by software (PQS)
Molecular Components in 1O6R
Label Count Molecule
Proteins (2 molecules)
2
Squalene--hopene Cyclase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
2
2
ALLYL-{6-[3-(4-BROMO-PHENYL)-BENZOFURAN-6-YLOXY]-HEXYL-}-METHYL-AMINALLYL-{6-[3-(4-BROMO-PHENYL)-BENZOFURAN-6-YLOXY]-HEXYL-}-METHYL-AMIN
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303