1RW8: Crystal Structure of TGF-beta receptor I kinase with ATP site inhibitor

PDB ID: 1RW8Download
MMDB ID: 31213
PDB Deposition Date: 2003/12/16
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 1RW8: monomeric; determined by author
Molecular Components in 1RW8
Label Count Molecule
Protein (1 molecule)
1
Tgf-beta Receptor Type I
(Gene symbol: TGFBR1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-(4-FLUOROPHENYL)-2-(6-METHYLPYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOLE3-(4-FLUOROPHENYL)-2-(6-METHYLPYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303