1S78: Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

PDB ID: 1S78Download
MMDB ID: 27406
PDB Deposition Date: 2004/1/29
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 3.25  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 1S78: trimeric; determined by author and by software (PISA)
Molecular Components in 1S78
Label Count Molecule
Proteins (3 molecules)
1
Receptor Protein-tyrosine Kinase Erbb-2
Molecule annotation
1
Pertuzumab FAB Light Chain
Molecule annotation
1
Pertuzumab FAB Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
6
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303