1T46: STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE

PDB ID: 1T46Download
MMDB ID: 28307
PDB Deposition Date: 2004/4/28
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 1T46: monomeric; determined by author
Molecular Components in 1T46
Label Count Molecule
Protein (1 molecule)
1
Homo Sapiens V-kit Hardy-zuckerman 4 Feline Sarcoma Viral Oncogene Homolog
(Gene symbol: KIT)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
PHOSPHATE IONPHOSPHATE ION
2
1
4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303