1TB6: 2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex

PDB ID: 1TB6Download
MMDB ID: 29032
PDB Deposition Date: 2004/5/19
Updated in MMDB: 2021/11
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 1TB6: trimeric; determined by author and by software (PISA)
Molecular Components in 1TB6
Label Count Molecule
Proteins (3 molecules)
1
Thrombin
(Gene symbol: F2)
Molecule annotation
1
Thrombin
(Gene symbol: F2)
Molecule annotation
1
Antithrombin-iii
(Gene symbol: SERPINC1)
Molecule annotation
Chemicals and Non-standard biopolymers (36 molecules)
1
7
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
alpha-L-fucopyranosealpha-L-fucopyranose
3
1
methyl 3-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranosidemethyl 3-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranoside
4
1
2,3-di-O-methyl-alpha-L-idopyranuronic acid2,3-di-O-methyl-alpha-L-idopyranuronic acid
5
2
2,3,6-tri-O-sulfo-alpha-D-glucopyranose2,3,6-tri-O-sulfo-alpha-D-glucopyranose
6
1
2,3-di-O-methyl-beta-D-glucopyranuronic acid2,3-di-O-methyl-beta-D-glucopyranuronic acid
7
2
2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose
8
4
2,3,6-tri-O-methyl-beta-D-glucopyranose2,3,6-tri-O-methyl-beta-D-glucopyranose
9
3
2,3,6-tri-O-methyl-alpha-D-glucopyranose2,3,6-tri-O-methyl-alpha-D-glucopyranose
10
1
2,3,6-tri-O-sulfonato-beta-D-glucopyranose2,3,6-tri-O-sulfonato-beta-D-glucopyranose
11
1
2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose
12
2
beta-D-mannopyranosebeta-D-mannopyranose
13
2
alpha-D-mannopyranosealpha-D-mannopyranose
14
8
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303