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1UWJ:
The complex of mutant V599E B-RAF and BAY439006
PDB ID:
1UWJ
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MMDB ID:
27132
PDB Deposition Date:
2004/2/5
Updated in MMDB:
2007/10
Experimental Method:
x-ray diffraction
Resolution:
3.5 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1UWJ: dimeric; determined by author and by software (PQS)
Molecular Components in 1UWJ
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
B-raf Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol:
BRAF
)
Chemicals and Non-standard biopolymers (2 molecules)
1
2
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303