2BFB: Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch

PDB ID: 2BFBDownload
MMDB ID: 37562
PDB Deposition Date: 2004/12/6
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.77  Å
Source Organism:
Similar Structures:
Biological Unit for 2BFB: tetrameric; determined by author and by software (PISA)
Molecular Components in 2BFB
Label Count Molecule
Proteins (4 molecules)
2
2-oxoisovalerate Dehydrogenase Alpha Subunit
(Gene symbol: BCKDHA)
Molecule annotation
2
2-oxoisovalerate Dehydrogenase Beta Subunit
(Gene symbol: BCKDHB)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
4
POTASSIUM IONPOTASSIUM ION
2
2
MANGANESE (II) IONMANGANESE (II) ION
3
4
CHLORIDE IONCHLORIDE ION
4
2
THIAMINE DIPHOSPHATETHIAMINE DIPHOSPHATE
5
2
GLYCEROLGLYCEROL
6
2
(4R)-2-METHYLPENTANE-2,4-DIOL(4R)-2-METHYLPENTANE-2,4-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303