2FO0: Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase

PDB ID: 2FO0Download
MMDB ID: 38294
PDB Deposition Date: 2006/1/12
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.27  Å
Source Organism:
Similar Structures:
Biological Unit for 2FO0: monomeric; determined by author
Molecular Components in 2FO0
Label Count Molecule
Protein (1 molecule)
1
Proto-oncogene Tyrosine-protein Kinase Abl1 (1B Isoform)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
MYRISTIC ACIDMYRISTIC ACID
2
1
6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE
3
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303