2J0F: Structural basis for non-competitive product inhibition in human thymidine phosphorylase: implication for drug design

PDB ID: 2J0FDownload
MMDB ID: 42474
PDB Deposition Date: 2006/8/2
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.31  Å
Source Organism:
Similar Structures:
Biological Unit for 2J0F: dimeric; determined by author and by software (PQS)
Molecular Components in 2J0F
Label Count Molecule
Proteins (2 molecules)
2
Thymidine Phosphorylase
(Gene symbol: TYMP)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
THYMINETHYMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303