2OPM: Human Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461

PDB ID: 2OPMDownload
MMDB ID: 61159
PDB Deposition Date: 2007/1/29
Updated in MMDB: 2007/12
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 2OPM: dimeric; determined by author and by software (PISA,PQS)
Molecular Components in 2OPM
Label Count Molecule
Proteins (2 molecules)
2
Farnesyl Pyrophosphate Synthetase (Fpp Synthetase) (Fps) (Farnesyl Diphosphate Synthetase) [includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)]
(Gene symbol: FDPS)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
PHOSPHATE IONPHOSPHATE ION
2
6
MAGNESIUM IONMAGNESIUM ION
3
2
3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303